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Blood routine is one of the must-see items for patients with rheumatic immune diseases, especially those who are newly diagnosed and treated
So what do the items in the blood routine mean?
The word "routine" is often translated as Routing, so the blood routine is often abbreviated to blood RT or Rt, including red blood cell count, white blood cell count, white blood cell classification count, hemoglobin number, platelet count and so on
Leukocyte abnormalities
Decreased white blood cell count
Commonly found in systemic lupus erythematosus, Sjogren's syndrome, mixed connective tissue disease, autoimmune hepatitis, and can also be seen in rheumatoid arthritis, also known as Felty syndrome
Increased white blood cell count
In almost every adult still patient, 75% of patients have leukocyte ≥ 15×109/L, and some patients even have naïve cells and present leukemia-like reactions, and may have high fever, rash, liver, spleen, lymphadenopathy, etc
Other rheumatisms that can cause mild increase in white blood cells are: rheumatic fever, polymyositis/dermatomyositis, systemic vasculitis including henoch-schönlein purpura, aortic arteritis, polyarteritis nodosum, Behcet's disease, allergic granulomatous vasculitis, etc
lymphocyte
Abbreviation: L% or LY%: increase is more common in viral infections
Neutrophils
Abbreviation: N% or NE%
Eosinophils
Abbreviation: E% or EO%
Eosinophilia: common in allergic diseases (bronchial asthma, urticaria, angioedema, food allergies, etc.
Eosinophilia: commonly seen on long-term treatment with adrenocorticosteroids, and in the early stages
Basophils
Abbreviation: B% or BA%.
Basophilia: common in chronic myelogenous leukemia, basophilic leukemia, myelofibrosis, and certain metastatic cancers
Red blood cell count
Increased red blood cell count
It can be seen in polycythemia vera, pulmonary heart disease, emphysema, and high altitude hypoxia
Decreased red blood cell count
It is common in systemic lupus erythematosus, with hemolytic anemia as the first symptom of systemic lupus erythematosus in many cases, others also seen in rheumatoid arthritis, Sjogren's syndrome, aortic arteritis, systemic sclerosis, polymyositis/dermatomyositis
Hemoglobin (also known as hemoglobin, Hb, or HGB)
Increased hemoglobin
Physiological increase, seen in highland dwellers, fetuses and newborns, strenuous activities, fear, cold water baths, etc.
Decreased hemoglobin
Physiologically reduced, the elderly due to the gradual decrease in bone marrow hematopoietic function, can lead to a decrease in the content of red blood cells and hemoglobin; Pathological decrease, bone marrow hematopoietic failure, such as aplastic anemia, myelofibrosis associated with anemia such as iron deficiency anemia, folic acid and vitamin B12 deficiency caused by megaloblastic anemia
Platelet count
increased platelet count (>300×109/L)
Common in rheumatoid arthritis, ankylosing spondylitis, reactive arthritis, etc
.
decreased platelet count (<100×109/L)
▶ Production disorders: seen in aplastic anemia, acute leukemia, acute radiation sickness
.
▶ Hyperlamination: seen in primary thrombocytopenic purpura and hypersplenism
.
▶ Hyperpendition: seen in diffuse intravascular coagulation (DIC
).
▶ Familial thrombocytopenia: macroplatelet syndrome
.
In rheumatism, it is common in systemic lupus erythematosus, and systemic lupus erythematosus with thrombocytopenia as the first symptom is not uncommon, and can also be seen in antiphospholipid syndrome, Sjogren syndrome, overlap syndrome, etc
.