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Duluth, Minnesota
Dr.
"We studied whether acute nicotine withdrawal increases the intake of high-salt, high-fat, and high-sugar junk food, and how the stress-relieving receptors of the opioid system are involved," al'Absi said
The research team conducted two laboratory studies on a group of smokers and non-smokers between the ages of 18 and 75
Smokers who are quitting nicotine consume more calories than non-smokers
Naltrexone normalizes calorie intake to the level of non-smokers, suggesting that the opioid system may be a mechanism by which withdrawal induces calorie intake
al'Absi and his team are currently focusing on the effects of changes in appetite on weight gain after quitting smoking, and the extent to which these changes hinder smoking cessation and increase the risk of relapse
al'Absi said: "These findings extend earlier studies that showed the effect of smoking on appetite and helped to determine an important biological link, namely the effect of the brain's opioid system on cravings during nicotine withdrawal
Co-authors include Dr.
This research was funded by R01DA016351 and R01DA027232 from the National Institute of Drug Abuse Grant al'Absi and Stress and Resilience Research Laboratory
DOI
DOI: 10.
Tobacco withdrawal increases junk food intake: The role of the endogenous opioid system
