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Radon is not only an important member of the soil ecosystem, but also known for its strong regenerative ability of the front and rear sections. why can the
regenerate the dragonfly? It's been a mystery until then.
, a recent study published in Nature Communication by the Kunming Institute of Zoology of the Chinese Academy of Sciences revealed the molecular cytology mechanism of radon regeneration.
the ability of animals to regenerate in nature has been a fascinating and complex biological process.
vertebrates such as zebrafish, dragonflies, geckos, can heal wounds and even regenerate lost hearts, tails, crystalline organs or appendages.
the "skills" of regenerating entire living organisms with small amounts of tissue and cells, and are also widely used in stem cell biology and regenerative medicine research.
, Darwin lamented in The Formation of Humus and the Role of The Earth: "It is difficult to find other creatures, like them, which, while seemingly humble, play such an important role in the course of world history."
" Wu Dongdong of the Kunming Institute of Zoology of the Chinese Academy of Sciences sequenced and assembled the high-quality Anderai-Sein-Sein genome at quasi-chromosomal levels, and revealed the molecular cytology mechanism of radon regeneration through the integration of bulk transcription groups (bulk sequencing) and single-cell transcription groups in different regeneration periods.
studies have found that the line2 transposon elements in the crucible genome may play an important regulatory role in radon regeneration, such as the line2 transposon elements being significantly and highly inserted into the differential gene sites associated with early regeneration of radon, and the line2 transposon sitelements expressed by some differences and their adjacent genes have very similar modes of expression.
team found that EGR1 (an early growth factor) of highly regenerative species such as the core regulatory vortex not only had a high lysis of high eras during radon regeneration, but also significantly different expression of line2 transposing elements on its flanks, so it was speculated that these significantly different expression elements might participate in the radon regeneration process by regulating adjacent genes.
on the other hand, the team found a large number of gene replication events in the radon genome, and these expanding gene families are mainly enriched in developmental biology pathways, and development and regeneration may often be common in certain pathways.
team also found that some significantly expanding gene families may regulate the regenerative process by increasing the dose effect of their copy count. In addition
, the analysis of single-cell transcription groups in the early stages of radon regeneration suggests that the high proportion of the cells that damage the healing site 72 hours after the early stage of radon regeneration are stem cells, and pluripotent stem cells play an important role in the early process of radon regeneration.
this study provides some candidate molecular cytology mechanisms for radon regeneration, and suggests that radon can be used as a new model for the study of regenerative biology or regenerative medicine.
Source: Science Daily.