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Early studies have shown that drinking coffee, taking aspirin, and smoking can affect the age of onset of Parkinson's disease (PD) and the degree of clinical symptoms
.
Yimaitong compiles and organizes, please do not reprint without authorization
.
Study Introduction This comprehensive study involved a total of 35,963 patients with idiopathic Parkinson's disease in the United States
.
Idiopathic Parkinson’s disease is the most common type of neurodegenerative disease, which hinders the brain’s ability to control movement
.
As the second most common neurodegenerative disease and the fastest growing neurological disease, PD currently affects more than 7 million patients worldwide
.
Genetic and environmental factors are considered to be factors affecting the age of onset
.
The researchers pointed out that although people already know the protective benefits of tobacco and smoking, the specific data on the age of onset is not comprehensive
.
Participants in the Fox Insight study-funded by the Michael J.
Fox Parkinson Research Foundation-answered the health and life>
.
Based on their answers, the researchers compared the median age of onset between different groups and found an exploratory association between life>
.
Research methods The duration of smoking, caffeine consumption, and aspirin intake are based on the age at which the patient started using any substance minus the end age
.
If the patient stops eating after the age of onset, the age at which they started is deducted from the age of onset
.
Researchers classified individuals as tobacco users who smoked more than 100 cigarettes in their lifetime, smoked at least one cigarette a day for at least 6 months, or used smokeless tobacco at least once a day for more than 6 months
.
Participants were considered coffee drinkers if they drank caffeinated coffee regularly at least once a week for at least 6 months
.
Participants are considered aspirin users if they have taken at least 2 aspirin a week for at least 6 months
.
Results of the study ➤The median age at the onset of tobacco use was later (63.
5 years), compared with 60.
8 years for non-smokers
.
The number of cigarettes smoked per day is also related to the later age of onset, although there is only a small difference
.
Similarly, the longer the smoking period, the positive correlation with the age of onset, but the effect size is also smaller
.
However, smoking is associated with more severe motor symptoms
.
Compared with non-smokers, smokers also reported anxiety, depression, and other non-motor symptoms, such as unexplained pain and memory problems
.
➤Patients who drink coffee often have a late onset of PD-61.
9 years old, while those who do not drink coffee are 59.
4 years old
.
The amount of coffee consumed per week may also have a small effect on coffee dosage, and is positively correlated with longer coffee drinking duration
.
In addition, drinking coffee is associated with less serious exercise scores
.
➤The age of onset of patients who took aspirin was 5 years later-64.
0 years old, while the age of patients who did not take aspirin was 59.
1 years old
.
However, after considering the comorbidities of heart disease and arthritis, the role of aspirin as an independent predictor of the onset of PD diminished
.
Expert comments Clemens Scherzer, MD, professor of neurology at Harvard Medical School in Boston, said, “It is known that drinking coffee and smoking are closely related to reducing the risk of PD, but the exact mechanism and chemical substances are still a mystery
.
” Perelman Medicine, University of Pennsylvania, Philadelphia Andrew Siderowf, MD, professor of neurology at the hospital commented, “The protective effects of smoking suggested by these results have not been proven.
The adverse health effects of smoking far outweigh any potential benefits of Parkinson’s disease
.
Therefore, Parkinson’s disease is recommended .
Don't smoke if you are sick
.
" Yimaitong compiled from: Coffee, Smoking and Aspirin Influence Parkinson's Disease Onset-Medscape-Nov 24, 2021.
.
Yimaitong compiles and organizes, please do not reprint without authorization
.
Study Introduction This comprehensive study involved a total of 35,963 patients with idiopathic Parkinson's disease in the United States
.
Idiopathic Parkinson’s disease is the most common type of neurodegenerative disease, which hinders the brain’s ability to control movement
.
As the second most common neurodegenerative disease and the fastest growing neurological disease, PD currently affects more than 7 million patients worldwide
.
Genetic and environmental factors are considered to be factors affecting the age of onset
.
The researchers pointed out that although people already know the protective benefits of tobacco and smoking, the specific data on the age of onset is not comprehensive
.
Participants in the Fox Insight study-funded by the Michael J.
Fox Parkinson Research Foundation-answered the health and life>
.
Based on their answers, the researchers compared the median age of onset between different groups and found an exploratory association between life>
.
Research methods The duration of smoking, caffeine consumption, and aspirin intake are based on the age at which the patient started using any substance minus the end age
.
If the patient stops eating after the age of onset, the age at which they started is deducted from the age of onset
.
Researchers classified individuals as tobacco users who smoked more than 100 cigarettes in their lifetime, smoked at least one cigarette a day for at least 6 months, or used smokeless tobacco at least once a day for more than 6 months
.
Participants were considered coffee drinkers if they drank caffeinated coffee regularly at least once a week for at least 6 months
.
Participants are considered aspirin users if they have taken at least 2 aspirin a week for at least 6 months
.
Results of the study ➤The median age at the onset of tobacco use was later (63.
5 years), compared with 60.
8 years for non-smokers
.
The number of cigarettes smoked per day is also related to the later age of onset, although there is only a small difference
.
Similarly, the longer the smoking period, the positive correlation with the age of onset, but the effect size is also smaller
.
However, smoking is associated with more severe motor symptoms
.
Compared with non-smokers, smokers also reported anxiety, depression, and other non-motor symptoms, such as unexplained pain and memory problems
.
➤Patients who drink coffee often have a late onset of PD-61.
9 years old, while those who do not drink coffee are 59.
4 years old
.
The amount of coffee consumed per week may also have a small effect on coffee dosage, and is positively correlated with longer coffee drinking duration
.
In addition, drinking coffee is associated with less serious exercise scores
.
➤The age of onset of patients who took aspirin was 5 years later-64.
0 years old, while the age of patients who did not take aspirin was 59.
1 years old
.
However, after considering the comorbidities of heart disease and arthritis, the role of aspirin as an independent predictor of the onset of PD diminished
.
Expert comments Clemens Scherzer, MD, professor of neurology at Harvard Medical School in Boston, said, “It is known that drinking coffee and smoking are closely related to reducing the risk of PD, but the exact mechanism and chemical substances are still a mystery
.
” Perelman Medicine, University of Pennsylvania, Philadelphia Andrew Siderowf, MD, professor of neurology at the hospital commented, “The protective effects of smoking suggested by these results have not been proven.
The adverse health effects of smoking far outweigh any potential benefits of Parkinson’s disease
.
Therefore, Parkinson’s disease is recommended .
Don't smoke if you are sick
.
" Yimaitong compiled from: Coffee, Smoking and Aspirin Influence Parkinson's Disease Onset-Medscape-Nov 24, 2021.
