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Gliclazide is suitable for mild and moderate non-insulin-dependent diabetes mellitus that is not satisfactory with diet control efficacy, and the patient's islet β cells have a certain insulin secretion function and no serious complications
.
It is mainly used for mild and medium-sized diabetes mellitus
that is ineffective with diet control alone and has no tendency to ketosis in adulthood.
It can also improve fundus lesions and metabolic and vascular function disorders in diabetics
.
It can be combined with biguanide oral hypoglycemic agents in patients who cannot be controlled alone, and in combination with insulin for the treatment of insulin-dependent diabetes, which can reduce the amount of
insulin.
So, can it also be used during pregnancy and lactation?
Pregnancy preparation: clinical data on the use of gliclazide in pregnant women with insulin
deficiency by replacing oral drugs, Data on other sulfonylureas are scarce
.
In animals, gliclazide is not teratogenic
.
To reduce the risk of congenital malformations in uncontrolled diabetes, diabetes
must be controlled before pregnancy.
Oral hypoglycemic agents during pregnancy are not suitable, so insulin is used as continued treatment
for diabetes.
It is recommended to switch oral hypoglycemic drugs to insulin therapy from the time when pregnancy is planned or when pregnancy is discovered
.
Can it be used during lactation?
Data
on the entry of gliclazide and its metabolites into breast milk are lacking.
Given the risk of hypoglycemia in newborns, the use of gliclazide
is contraindicated in lactating women.
Where can I find more information on pregnancy/lactation medication?
What drugs should not be touched during pregnancy? What medications are secreted through breast milk?
Scan the code to download the clinical decision-making app
in 3 steps Rapid access to safe medication information during pregnancy/lactation References:[1] Drug information
: gliclazide sustained-release capsules
, Hangzhou Guoguang Pharmaceutical Co.
, Ltd.
, Sinopharm H20070261; 2012/11/13.
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