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    Home > Active Ingredient News > Immunology News > When RA encounters LTBI, how to break through the treatment bottleneck?

    When RA encounters LTBI, how to break through the treatment bottleneck?

    • Last Update: 2022-10-13
    • Source: Internet
    • Author: User
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    If csDARD and bDMARD treatment is ineffective in RA patients with LTBI, can tsDMARD bring improvement?


    Rheumatoid arthritis (RA) is one of the common systemic rheumatism diseases in China, and the prolonged course of the disease and the high disability of the disease make patients miserable, but also bring a heavy burden to families and society [1].

    In recent years, with the development of innovative drugs such as baritinib and tofatib, the RA treatment track has continuously emerged with diversified treatment options
    .
    For clinicians, how to weigh efficacy and safety and provide patients with more rational treatment decisions has become a compulsory course
    .


    "The population base of tuberculosis patients in China is large, and RA patients, as a high-risk group, have a 4-fold increase in the risk of tuberculosis infection compared with the general population [2]
    .
    " Professor Chen Jinwei of the Second Xiangya Hospital of Central South University pointed out, "With the increasing prevention and management of tuberculosis in RA patients, the treatment options for such patients in the clinic have gradually become the focus and exploration of rheumatologists
    .
    There is no doubt that the early diagnosis and treatment of latent tuberculosis infection (LTBI) is key to preventing the resurgence of tuberculosis and effectively controlling TB [3].


    Professor Chen Jinwei will share his diagnosis and treatment ideas and experience
    with more clinicians through an RA case with LTBI.



    Click [Read the original article], learn more immediately, full of dry goods, not to be missed! The patient has obtained informed consent in
    this case.

    References:[1] Rheumatology Branch of Chinese Medical Association.
    Chinese Journal of Internal Medicine,2018,57(4): 242-251.
    [2] Carmona L ,et al.
    Journal of Rheumatology, 2003, 30(7):1436-9.
    Huang Anfang, et al.
    Chinese Journal of Internal Medicine,2016,55(4): 307-310.

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