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According to public information and query the Yaozhi database (global best-selling drug sales database), we summarize and analyze the 10 years of global sales of TOP100 drugs.
The sales of TOP100 drugs have continued to grow in the past 10 years, with a 10-year compound growth rate (CAGR) of 2.
7 %
.
In the past 10 years, the sales of TOP100 drugs have increased by 565.
Figure 1 2011-2020 global sales statistics of TOP100 drugs
Data source: Yaozhi global best-selling drug sales database, compiled by Yaozhi Consulting
Major pillar drugs classified by ATC
Major pillar drugs classified by ATC 1.
Immunosuppressant
Figure 2 2011-2020 global sales statistics of immunosuppressive drugs in TOP100 drugs
Data source: Yaozhi global best-selling drug sales database, compiled by Yaozhi Consulting
Immunosuppressants can reduce human immunity.
In terms of anti-tumor, immunosuppressants are used very frequently.
Commonly used drugs are ulinumumab and lenalidomide; in the treatment of rheumatism, doctors often use them.
"Immunosuppressive agents"
.
The immune function of patients with rheumatic immunological diseases is often activated abnormally, leading to excessive immunity.
The reason for the high market sales of immunosuppressive drugs in the past 10 years is still because of "cancer
.
" According to research, in our country, about 80 million people die of cancer every year, and 6-7 people are diagnosed with cancer every minute.
In summary, immunosuppressive agents are mainly used in rheumatic immune diseases and anti-tumor diseases.
However, due to the bad environment, unhealthy diet and modern fast-paced life and other factors, immunosuppressive drugs have shown an increasing trend in the past 10 years
.
2.
Protein kinase inhibitor
Protein kinases can regulate all aspects of cells.
Abnormal expression levels or mutations can lead to cancer and other diseases.
Since the approval of imatinib in 2001, 76 kinase inhibitors have been approved for marketing.
These pioneering compounds have successfully changed People's view of protein kinase as a drug target
.
The development and approval of kinase inhibitors has changed the clinical treatment of various malignant tumors such as melanoma.
In the final analysis, among protein kinase inhibitors, whether it is ibrutinib, imatinib or even everolimus, they all present a common feature that is the treatment of tumor drugs
Figure 3 2011-2020 global sales statistics of protein kinase inhibitors in TOP100 drugs
Data source: Yaozhi global best-selling drug sales database, compiled by Yaozhi Consulting
Unexpected performance of vaccine drugs
Unexpected performance of vaccine drugs1.
Figure 4 2011-2020 global sales statistics of viral vaccines among TOP100 drugs
Data source: Yaozhi global best-selling drug sales database, compiled by Yaozhi Consulting
Viral vaccine products among the TOP100 drugs that have entered global sales include shingles vaccine, influenza vaccine, and human papillomavirus vaccine.
Summarize
SummarizeFrom the perspective of global TOP100 sales of drugs from 2011 to 2020, the sales amount of anti-tumor drugs reached 100 billion yuan, occupying 50% of the global sales of TOP100 drugs.