What is peptide raw material? What is the value of good peptide raw material
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Last Update: 2019-07-26
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Source: Internet
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Author: User
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Peptide raw material is peptide First of all, I will introduce peptide to you Peptide raw material is a kind of physiological substance existing between amino acid and protein Amino acid molecule is the smallest and protein is the largest More than two amino acids dehydrate and condense to form peptide bond, so many peptide bonds will be organized into a peptide, Peptide raw material products have chemical traces and residues, which are difficult to form functions, and it is difficult to realize industrial production Up to now, they still stay in the laboratory Alkali method, the method of catalyzing protein with chemical alkali, is called alkali method Most of this method is the same as acid, and the same peptide raw material can not avoid the same result, that is, stay in the laboratory Peptide raw materials can be hydrolyzed from dietary protein by chemical method or obtained by artificial method It is composed of two or more amino acids The synthesis of peptide raw materials is very important in the regulation of cell physiology and metabolic function The properties of peptide raw materials are relatively unstable Long-term storage is suitable for moistureproof There are many traditional methods for peptide preparation when it is placed below the fourth degree I'd like to introduce a special point for you The method of using chemical strong acid to catalyze protein to obtain peptide is called acid method, which is characterized by large investment, large area, complex process, large pollution and difficult to control molecular weight I believe that there will be better technology in the future to make contributions to people's industry or related industries The method of electricity and protein electrolysis is called electricity Peptide raw materials do not have obvious advantages and functions, so few people study and use it Peptide raw materials are also the reports of industrial production Artificial grafting method is the amino acid produced by fine chemical industry, with options For directional grafting, this method is generally used to operate the machine, with a large production, but the peptide produced has no activity, the physiological function of peptide raw material is not obvious, gene expression method, the method of separating and extracting from animal blood or tissue, collectively referred to as gene expression method, so the method is important for the research and production of peptide drugs, peptide raw material and its representative products are thymosin peptide , thymopentin Interferon, interleukin-11, interleukin-111, human serum albumin, immunoglobulin, gamma globulin, tumor necrosis factor and other important roles Enzyme method: enzyme method is called enzyme method Enzyme method has a greater breakthrough and innovation on the basis of tradition Peptide raw materials meet the requirements of low-carbon economy and green environmental protection Enzyme method is to use enzyme to catalyze protein to obtain peptide, which means protein degradation, synthetic peptide, acid method and enzyme method Alkaline method, mild and environmental protection, simple production process, less investment, quick effect, suitable for industrial production, enzyme method to obtain peptide molecular weight easy to control, peptide raw material product itself rich in green attributes, active peptide, nutrition, hormone, enzyme inhibition, immune regulation, antibacterial, antiviral, peptide raw material antioxidant are very closely related Polypeptides are generally divided into: polypeptide drugs and polypeptide health products The traditional peptide drugs are mainly peptide hormones In recent years, peptide materials have developed into various fields of disease prevention and treatment, especially in the following fields The receptor of known cytokines is used to simulate peptide from peptide library This year, it has become a research feature at home and abroad The peptide raw material has been screened for human erythropoietin abroad The main use of polypeptide in diagnostic reagents is to be used as an antigen to detect antibodies of corresponding pathogenic organisms The peptide antigen is more specific than the natural microorganism or parasite protein antigen, and is easy to prepare Now the antibody detection reagents assembled with polypeptide antigens include: A, B, C, G liver disease virus, HIV, human cytomegalovirus, herpes simplex virus, rubella virus, Treponema pallidum, cysticercosis, Lyme disease, rheumatoid and other detection reagents Most of the peptide antigens used in peptide raw materials are obtained from the natural protein internal analysis of the corresponding pathogenic body, and some of the peptide raw materials are brand-new peptides screened from the peptide library In the early years, all the medicinal peptides were prepared from natural organs or corresponding tissues by extraction and purification The production process of peptide raw materials is complex, not easy to master, and easy to contain some impurities with other functions In recent years, the method of chemical synthesis of peptides has made great progress The peptide raw materials industry has been able to provide cheap amino acids, and the production of peptide drugs has been gradually converted to chemical synthesis Production by law Generally speaking, drugs less than 20 peptides can be produced by chemical methods, such as oxytocin The principle of using genetic engineering to produce active peptide has been solved, and it may be formally applied in production in the near future Up to now, polypeptide Kang elements are mainly produced by fermentation So peptide raw materials are formed in this way, and we need to use them together.
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