What harm will air pollution do to human health?

In this paper, several research results are compiled to analyze the harm of air pollution to human health? Learn with you! Photo source: Wikipedia commons [1] epidemiology: the first discovery of the relationship between air pollution and brain cancer doi: 10.1097/ede.0000000000001137 in a new study, researchers from the University of McGill and other research institutions in Canada found for the first time that ultrafine particles produced by fuel combustion are related to the production of malignant brain tumors The results, recently published in the journal Epidemiology, have shown that these combustion related nanoparticles reach the human brain when inhaled The researchers analyzed the medical records and air pollution exposure of 1.9 million adults in Montreal and Toronto, Canada They found that an increase of 10000 nanoparticles per cubic centimeter of air pollution could lead to another brain cancer in every 100000 people exposed to the air pollution This increase in air pollution is equivalent to walking from a quiet city street to a busy street The researchers measured malignant tumors in the brain, including glioblastoma, the most common form of brain cancer, which affects about three out of 100000 people in the United States 【2】 Ecolog Economy: new discovery! Is there a link between air pollution and impaired memory? Evidence on 34000 English cities recently published in the international journal economic In the Research Report on economics, scientists from Warwick University found that people's memory tends to be significantly worse in areas with high content of nitrogen dioxide (NO2) and air particles (PM10) in the UK The difference in memory level between people in the cleanest and most polluted areas in the UK is equivalent to the memory loss caused by aging for 10 years This is consistent with previous small-scale experiments on mice and other animals, in which the same results were observed for the first time in humans In this paper, the researchers randomly studied 34000 British citizens Each participant was asked to remember 10 words in a standardized word recall test In the analysis, the researchers considered a variety of factors affecting people's memory quality, including age, health, education, race, family and employment The results revealed air pollution and people Group memory impairment is closely related 【3】 I can't hurt you! How could air pollution cause hair loss! News reading: air pollution linked to hair loss, a study released recently at the 28th eadv conference in Madrid shows for the first time that exposure to common air pollutants, particulate matter (PM), is related to human hair loss This study was conducted by exposing the cells at the bottom of human scalp hair follicles, namely human hair follicle dermal papilla cells (hfdpcs), to PM10 like dust and diesel particles of different concentrations After 24 hours, the researchers carried out western blotting to detect the level of specific proteins in cells The results showed that PM10 and diesel particles reduced the level of β - Catenin, a protein responsible for hair growth and morphogenesis PM10 like dust and diesel particles can reduce the levels of three other proteins (cyclin D1, cyclin E and CDK2) responsible for hair growth and maintenance in a dose-dependent manner, which means that the higher the level of pollutants, the more significant the decrease in protein level 【4】 JAMA network open: scientists clarify the relationship between air pollution and the risk of coronary atherosclerosis in Chinese population doi: 10.1001/jamanetworkopen.2019.6553 recently, an international journal JAMA network In the Research Report on open, scientists from the University of buffalo and other institutions provided solid pathological evidence through research to clarify the impact of air pollution on cardiovascular disease in Chinese population Relevant research results showed that China may need to revise the standards for one of the pollutants In this paper, 8867 Chinese adults aged 25-92 years were studied and found that long-term exposure to particulate matter, nitrogen dioxide, vehicles or vehicles was related to the degree of coronary artery calcification and plaque accumulation in the arterial wall The results of this study are of great significance, because similar studies have only been carried out in the United States and Europe before, but this paper The study is the first in a Chinese population to examine the association between air pollution and coronary artery calcification In recent years, China has focused on how to reduce high air pollution in some areas, especially in northern China; researcher Meng Professor Wang said that this study provides some evidence that the exposure of air pollutants to coronary atherosclerosis or a pathological manifestation will increase the risk of death due to coronary heart disease in the population At the same time, this study can help understand the impact of air pollution on the health of the global population, which provides some support for the development of global air pollution standards Evidence and underlying data 【5】 Alert! Air pollution will affect women's fertility! News reading: air pollution found to affect market of female fertility in real life study a large-scale study found that serious air pollution has a negative impact on ovarian reserve Ovarian reserve is a widely used term to reflect the number of resting follicles in the ovary, so it is a sign of women's potential fertility The ovarian reserve and exposure to environmental pollutants (orexpo) study is a real-world study that analyzes hormone test data from more than 1300 Italian women Behind this research, there is more and more evidence that many environmental chemicals, as well as natural and artificial ingredients in daily diet, may interfere with the physiological function of hormones, their biosynthesis, signaling or metabolism AMH is secreted by ovarian cells and is widely considered as a reliable marker of ovarian reserve Source: Yale University [6] Cardiov Toxicol: air pollution may affect the health of fetal cardiovascular system doi: 10.1007/s12012-019-09505-0 In the Research Report on toxicology, scientists from Rutgers University found that inhalation of tiny particles in the air may damage the function of fetal cardiovascular development system in pregnant women The researchers pointed out that the early and late stages of pregnancy are very critical periods, during which pollutants have the greatest impact on the health of pregnant women and fetal cardiovascular system Researcher Phoebe Professor Stapleton said that the results of this study show that pregnant women, pregnant women and women undergoing fertility treatment should try to avoid areas with serious air pollution, or stay indoors when the haze is serious, so as to avoid exposure to polluted air particles In addition, pregnant women should especially consider monitoring indoor air quality, and the particles inhaled by pregnant women will affect their mechanism The circulatory system of the body will continuously provide nutrition for the fetus in the process of growth and development 【7】 Jah: air pollution can affect future generations' Health News Reading: dirty air now could harm hearts of offspring later a new animal study shows that parents' exposure to dirty air before conception may cause heart disease to the next generation To understand the possible health risks for children who are often exposed to highly polluted air, researchers at Ohio State University studied the effects of dirty air on mice We found that these descendants had all kinds of heart problems in the golden age of their lives, and their impact was very strong, a little shocking " The main health problem is impaired heart function Inflammatory markers associated with increased risk of heart disease are high They have markers of oxidative stress, a state of low levels of beneficial antioxidants The calcium regulatory proteins, which are essential for breast-feeding heart function, were altered in these young, healthy mice - comparable to those of a 20-year-old human The researchers say that heart problems associated with contamination may even begin before pregnancy, and if that's true, it could have an impact worldwide In addition, the researchers found evidence of gene related differences that may explain the cardiovascular changes they saw They studied epigenetic regulators, which play an important role in gene expression - which means they have an impact on susceptibility to health problems, including cardiovascular disease [8] J Invest Med: air pollution will increase the incidence rate of oropharyngeal cancer Doi:10.1136/jim-2016-000263 high level of air pollutants, especially fine particulate matter (PM2.5) and lesser ozone, may be related to increased risk of oral cancer, the study is published online in Journal of Investigative Medicine magazine In many parts of the world, the number of new cases and deaths from oral cancer is increasing Known risk factors include smoking, drinking, human papillomavirus, and areca eating habits in parts of Southeast Asia It is also believed that exposure to heavy metals and emissions from petrochemical plants are related to the development of diseases, while air pollution, especially PM2.5, is known to be harmful to respiratory and cardiovascular health To determine whether air pollutants may play a role in the development of oral cancer, the researchers analyzed data from the national cancer, health, insurance and air quality databases In 2012 - 13, 1617 cases of oral cancer were diagnosed in men As expected, smoking and frequent betel nut chewing were significantly associated with increased risk of diagnosis, as were high levels of PM2.5 After considering the potential influencing factors, the increase of PM2.5 level is related to the increased risk of oral cancer 【9】 PLoS One: bad kidney? It may be due to air pollution! Doi: 10.1371/journal.pone.0200612 there are regional differences in the prevalence of chronic kidney disease (CKD) in the United States Although some of the differences can be explained by differences in patient risk factors, there are significant unexplained differences The researchers speculate that this may be due to other environmental factors that have not been studied, such as air pollution To this end, the researchers used the data of 1.1 million people in 2010 medical insurance samples and Environmental Protection Agency air quality measures to test the relationship between PM2.5 particles in the county level air and the confirmed prevalence of CKD The researchers used the modified Poisson regression model to evaluate the relationship between PM2.5 concentration in the county level and CKD level of individual patients, and corrected the relationship between PM2.5 concentration in the county level and CKD level Age, gender, race, hypertension, diabetes and economic status 【10】 Int J Epidemiol: results of a birth cohort study from China: high levels of air pollutants or a direct correlation with abnormal fetal growth doi: 10.1093/ije/dyy019 recently, an International Journal of In the Research Report of epidemiology, researchers from Yale University School of public health and other institutions found that exposure to specific air pollutants during pregnancy may increase