What can we learn from the collaborative innovation development results of the biomedical industry in the Chengdu-Chongqing Economic Circle

China's biomedical industry has initially formed an industrial cluster centered on the Yangtze River Delta, Beijing-Tianjin-Hebei, Guangdong-Hong Kong-Macao Greater Bay Area and Chengdu-Chongqing region
.

On October 20, 2021, the Central Committee of the Communist Party of China and the State Council issued the "Plan for the Construction of the Chengdu-Chongqing Double City Economic Circle", proposing to coordinate the development of biomedicine, medical equipment, and modern Chinese medicine industries to jointly build a large western health industry base

01 The development pattern of the biomedical industry in Chengdu and Chongqing

01 The development pattern of the biomedical industry in Chengdu and Chongqing

1.
Release policy dividends and optimize industrial quality

In recent years, Chengdu has actively promoted the high-quality development of the biopharmaceutical industry, and in 2019 issued the "Implementation Opinions on Promoting the High-quality Development of Chengdu's Pharmaceutical and Health Industry" and "Policies for Promoting the High-quality Development of Chengdu's Biopharmaceutical Industry".
Established a world-class highland for the medical and health industry, building Chengdu into a global biomedical innovation and creation center, the first choice for medical and health services for the “Belt and Road” initiative, and a hub city for the international pharmaceutical supply chain
.

Chongqing attaches great importance to the development of the biopharmaceutical industry and regards it as one of the top ten strategic emerging industries in the city, which is included in the pillar industry to focus on building.
In 2025), it is proposed that by 2025, a health industry system with rich content and reasonable structure will be basically formed, and efforts will be made to build Chongqing into a national medical city, a medical highland in the west, an important national medical base and an internationally renowned health resort
.

2.
The industry is developing rapidly, showing a trend of agglomeration

At present, the biomedical industry in Chengdu-Chongqing is developing rapidly, and it is showing a trend of regional agglomeration
.

Among them, Chengdu proposes to build a world-class, trillion-level modern medical and health industry system, focusing on key areas such as biomedicine, medical health, and pharmaceutical commerce

Figure 1: Positioning of key biomedical industrial parks in the Shuangcheng Economic Circle of Chengdu-Chongqing Region

Source: Chongqing Municipal Planning and Natural Resources Bureau, Flint Creation

3.
Cluster of innovation achievements, frequent heavy products

According to the Firestone Creation Database, in the field of medical and health patents, as of the end of September 2021, the cumulative number of patents related to the biomedical industry authorized by medical and health companies and institutions in Chengdu and Chongqing were 21,542 and 20,647 respectively
.

In the pharmaceutical field, as of the end of September 2021, Chengdu and Chongqing have the Drug Evaluation Center (CDE) of the National Medical Products Administration (CDE) accepting 430 and 180 new drugs (category 1 and 2) respectively, and the number of domestic drugs approved respectively There are 4165 and 3659 pieces

4.
Convergence of innovative elements to activate the source of innovation

According to the Flint Creations database, as of the end of September 2021, Chengdu and Chongqing have gathered 62699 and 53,040 pharmaceutical and health companies, and 27 and 20 biomedical listed companies, respectively, in terms of corporate entities, forming a strong support capacity for innovation entities
.

In terms of scientific research institutes, as of the end of September 2021, Chengdu and Chongqing have 44 and 29 medical universities, respectively, as well as the State Key Laboratory of Biotherapy, the State Key Laboratory of Oral Disease Research, and the National Engineering Research Center for Ultrasound Medicine.

02 The practice and experience of collaborative innovation and development of biomedical industry in Chengdu-Chongqing Economic Circle

02 The practice and experience of collaborative innovation and development of biomedical industry in Chengdu-Chongqing Economic Circle

1.
National policies to promote the integrated and integrated development of the regional biomedical industry

The construction of a dual-city economic circle in the Chengdu-Chongqing region has become a national strategy to promote the coordinated development of the pharmaceutical and health industry
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In 2011, the State Council approved the implementation of the "Regional Plan for Chengyu Economic Zone", clearly requiring that the Chengyu Economic Zone be built into an important economic center in the western region and promote national regional coordination

2.
Cut into characteristics and promote the integrated development of Chinese medicine industry, industry and culture

Strengthen collaboration and cooperation with characteristic industries of traditional Chinese medicine
.

In May 2020, Sichuan Provincial Administration of Traditional Chinese Medicine and Chongqing Administration of Traditional Chinese Medicine signed a cooperation agreement on the integrated development of Sichuan and Chongqing Traditional Chinese Medicine

3.
Demonstration of cross-regional cooperation in advance to promote in-depth cooperation in all dimensions and in multiple fields

The first is to jointly build a high-level cooperation carrier and promote in-depth cross-regional, comprehensive and multi-field cooperation
.

For example, in May 2020, Chengdu and Yibin cities signed the "Chengdu Municipal People’s Government and Yibin Municipal People’s Government to Promote the Construction of the Chengdu-Chongqing Double-City Economic Circle and Jointly Build a Pilot City for Cross-Regional Cooperation".

The second is to explore the industrial interaction model of "headquarters + base", "R&D + production" and "product + market" to promote in-depth cooperation in the biomedical industry
.

For example, in 2017, Chengdu and Neijiang signed a strategic cooperation agreement to promote coordinated development, supported the establishment of the province’s first "Rongou+" ASEAN international train base in Neijiang, and jointly launched the Chengdu-Neijiang-ASEAN sea-rail combined train to drive Neijiang.

4.
Build a collaborative innovation service system and optimize the regional innovation and entrepreneurship ecological environment

Work together to build a cross-regional industrial ecosystem
.
In August 2019, the two cities of Chengde jointly issued the "Chengde Industrial Co-City Development Plan (2019-2022)", proposing to build a coordinated regional development mechanism as a starting point to form resource sharing, mechanism co-construction, industrial symbiosis, and cooperation A new pattern of win-win industrial co-city development, and jointly build a cross-regional industrial ecosystem
.
In May 2020, Mianyang City and Chongqing Beibei District Science and Technology Bureau signed the "Cooperation Agreement on Promoting the Construction of the Bi-city Economic Circle in Chengdu-Chongqing Region" to jointly promote the construction of a regional collaborative innovation system, jointly advance scientific and technological collaborative innovation research, and jointly promote the transformation of scientific and technological achievements Work together with industrialization and jointly promote the innovation and entrepreneurship environment, focusing on the national dual-use technology trading center and the large-scale scientific instrument sharing platform in Sichuan to carry out joint construction and sharing cooperation, mutual recognition and exchange of science and technology innovation policies between the two places, and jointly apply for major national and provincial scientific and technological projects In-depth cooperation in other areas
.

5.
The integrated development of industry, university, research and medicine will enhance the overall technological innovation level of the region

Industry-university-research-medicine collaboration to build an integrated collaborative innovation system
.
For example, in August 2020, during the second Chongqing Bi-monthly Forum on the Integration of Science and Technology and Economy, universities, enterprises, and medical institutions in Sichuan and Chongqing signed a number of biomedical cooperation agreements to promote collaborative innovation and cooperation in the biomedical industry
.
Including co-construction of Sichuan-Chongqing Oncology Collaborative Innovation Center (Chongqing) Research Institute, strengthening project cooperation and achievement transformation, co-organizing industry and academic high-end forums, talent exchange training and other aspects of cooperation, actively constructing basic research, key technology research, achievement transformation, The whole chain and integrated collaborative innovation system of industrial manufacturing; Chongqing International Bio-City Development Investment Co.
, Ltd.
and West China College of Pharmacy, Sichuan University signed a strategic cooperation framework agreement, and the two parties jointly established the Chongqing Pharmaceutical Manufacturing Engineering Research Center for APIs and drug intermediates And high-end new preparations to carry out technological research and industrial transformation; Sichuan-Chongqing Medical and Edible Fungus Resource Development Center and Chongqing Biomedicine "Two Studies and One Production" Consortium were awarded the license to open up communication channels for societies, universities and enterprises to realize resources Sharing and mutually beneficial cooperation to promote biomedical technology innovation and industrial development
.

6.
Promote the free flow of innovative elements and realize resource sharing and complementary advantages

In terms of the flow of scientific and technological resources, in April 2020, Chongqing Science and Technology Bureau and Sichuan Provincial Science and Technology Department signed the “Framework Agreement on Further Deepening Sichuan-Chongqing Science and Technology Innovation Cooperation and Enhancing Collaborative Innovation Development Capabilities to Build a Nationally Influential Science and Technology Innovation Center” and “Science and Technology Resource Sharing” Cooperation Agreement", "Special Cooperation Agreement for Coordinating the Transformation of Scientific and Technological Achievements", "Science and Technology Expert Database Open and Sharing Cooperation Agreement", etc.
The two parties will build a regional collaborative innovation system and promote the formation of a regional scientific and technological innovation platform, resource sharing, project promotion, and policy sharing , Achievement sharing situation; through the creation of the “Sichuan-Chongqing science and technology resource sharing service platform”, a “one platform, two base” pattern based on Chongqing and Chengdu bases will be formed; more than 30,000 science and technology expert databases in the two places will be open and shared.
Open up the docking channel between technical needs and expert services; promote the interconnection of the transfer and transformation of scientific and technological achievements in the two places, and build a group of high-level technology transfer institutions, cultivate a group of professional technical managers, and provide professional services for the transfer and transformation of scientific and technological achievements
.

In terms of human resource flow, in April 2020, Chongqing Human Resources and Social Security Bureau and Sichuan Provincial Human Resources and Social Security Department signed the "Jointly Promoting the Construction of the Chengdu-Chongqing Double-city Economic Circle in Sichuan-Chongqing Human Resources and Social Security Cooperation Agreement.
" The two places jointly optimize the allocation of human resources market factors, promote the coordination of public employment and entrepreneurship services, deepen the cooperation in the service guarantee of migrant workers, promote the coordination of social insurance services, promote the cooperation of skilled personnel training, promote the coordination of professional and technical personnel, and promote the major public policies of the human resources and social society.
Seven cooperations including the coordination of safeguard measures
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In terms of market supervision integration, in May 2020, the Chengdu High-tech Zone Market Supervision Bureau and the Chongqing High-tech Zone Market Supervision Bureau signed the “Framework Agreement on Deepening Chengdu-Chongqing High-tech Market Supervision Integration and Boosting the Construction of Science City in Western China” to build a cross-regional market The access service system and the "market access in different places with the same standard" facilitated access mechanism to realize the mutual issuance of certificates and licenses in different places
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In terms of the integration of public affairs and services, in June 2020, Chengdu High-tech Zone signed a cooperation agreement with Chongqing High-tech Zone Public Service Bureau, Chongqing High-tech Zone Government Service and Social Affairs Center to jointly promote the integrated development of education, medical and health services in Chengdu and Chongqing.
Cooperate and share in civil affairs, cultural tourism, talent mobility, employment and entrepreneurship, medical insurance and social insurance, and intelligent construction, establish a cooperative and interactive mechanism, and build a new pattern of integrated development of social affairs and public services
.

In terms of co-construction and sharing of educational resources, in October 2020, initiated by Sichuan International Studies University, Sichuan University, University of Electronic Science and Technology, Chongqing University, Southwest University and other universities in Chengdu and Chongqing have established foreign language disciplines, as well as 23 representatives from provinces along the new western land-sea corridor.
Colleges and universities jointly formed the Foreign Language Alliance of Colleges and Universities in the Chengdu-Chongqing Double City Economic Circle to eliminate subject barriers and promote the co-construction and sharing of foreign language resources
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In terms of innovative financial flows, in October 2020, Chongqing High-tech Zone, Bishan District, Yufu Holdings, Real Estate Group, Sichuan Development, etc.
jointly funded the establishment of the Chengdu-Chongqing Region Twin City Economic Circle Development Fund, with a total scale of 30 billion yuan, committed to investment The strategic emerging industries represented by biomedicine and general health in Sichuan and Chongqing have promoted the benign flow of high-quality enterprises in the two cities, and promoted the improvement of quality and efficiency, transformation and upgrading of the real economy in Sichuan and Chongqing
.

03 Proposals for the integrated development of biomedical industry in Chengdu-Chongqing Economic Circle

03 Proposals for the integrated development of biomedical industry in Chengdu-Chongqing Economic Circle

In general, the key cities in the development of the biomedical industry in the Chengdu-Chongqing Economic Circle mainly focus on policy guidance, cooperation in characteristic industries, cross-regional pilot cooperation demonstrations, integrated development of industry-university-research-medicine, construction of a regional collaborative innovation system, and promotion of the free flow of innovative elements.
On the one hand, actively promote the collaborative and innovative development of the cross-regional biomedical industry
.
Facing the future, the author believes that the internationalization, high-quality, and integrated development of the biomedical industry in the Chengdu-Chongqing Economic Circle still need to focus on the following five directions:

First, based on the geographical location of the Chengdu-Chongqing economic circle, river, sea, land and air transportation, and the advantages of industrial resources in various regions, "leverage" the opportunity of reshaping the global industrial chain, accelerate the international layout, and increase the integration of local and global high-quality innovative resources to create The innovative resource service platform for the biomedical industry in the Chongqing Economic Circle will improve the quality and level of the coordinated development of the industry while fully connecting with the international market
.

The second is to leverage the Chengdu-Chongqing economic circle as the back of the national strategy, and focus on innovation ecologicalization, to build a bio-economic ecosystem integrating innovation chain, industrial chain, space chain, service chain, and capital chain, and create a co-frequency The resonant industrial innovation development atmosphere links the biomedical industry clusters in the Beijing-Tianjin-Hebei, Yangtze River Delta, and Guangdong-Hong Kong-Macao Greater Bay Area to jointly build the "basic plate" of China's big health industry innovation ecology
.

The third is to combine the manufacturing space and cost advantages of the Chengdu-Chongqing Economic Circle relative to the eastern region, as well as the medical, education, and scientific research resources advantages of the western region, scientifically and rationally plan the layout of the biomedical industry in various regions, precise positioning, precise introduction, and speed up biomedicine The integrated development of the industry and the digital economy will derive new industries, new business forms, and new models, and form a number of specialized and new industry projects to enhance the added value of the regional biopharmaceutical industry and the absorption capacity of high-precision subdivisions
.

The fourth is to deal with the status quo of Chengdu-Chongqing dual-core dominance and unequal development of sub-cities, strengthen the coordination of reforms, and establish synergistic effects for biomedical industry cities and parks at different development stages, development levels, development fields, and development models.
Mechanisms, first trial system arrangements, etc.
, to create a "fourth pole" for the high-quality development of China's biomedical industry
.

Fifth, give full play to the guiding role of the Chengdu-Chongqing Economic Circle Development Fund, build a biomedical innovation center in the Chengdu-Chongqing Economic Circle, focus on basic research and source innovation of new drugs and innovative medical devices, and coordinate to enhance independent innovation capabilities to form a Chongqing economy The cooperative development alliance of the circle pharmaceutical industry park establishes an effective work coordination mechanism, information communication, and a strong synergy, plans major national and provincial industrial development projects, and creates an excellent regional industrial innovation and development environment
.