What are the inhibitory effects of bioactive peptides on tumor?

Tumor refers to the mature or developing normal cells in the body, under the influence of relevant factors, showing excessive growth or abnormal differentiation in the formation of new organisms Tumor is a common disease, which seriously threatens human health and life In many countries, the death rate of malignant tumor is second only to that of heart disease, which is the leading cause of death In China, malignant tumor is also the main cause of death At present, the common chemotherapy and radiotherapy for cancer patients often lead to serious side effects, so it is one of the hot spots to find high-efficiency and low toxicity anti-tumor drugs, and the new bioactive peptides just have these characteristics Bioactive peptides are widely found in nature and can be synthesized by artificial methods Because of their low molecular weight, high activity and low toxicity, they have important value in the clinical treatment of tumors Peptide with tumor inhibitory effect is called tumor inhibitory peptide At present, some tumor inhibitory peptides are not limited to the nutrients with tumor inhibitory effect They have developed into anti-tumor drugs, and become the research hotspot of searching for anti-cancer drugs For example, for the treatment of digestive system, the growth inhibition of endocrine tumor is a peptide drug Inhibitory effect of bioactive peptide on tumor 1 Direct inhibition of tumor growth 2 Inhibition of tumor metastasis 3 Inhibition of tumor angiogenesis 4 Mobilizing the immune system to inhibit tumor growth 5 Antioxidation and radiation damage resistance 6 Interfering with DNA synthesis of tumor cells 7 Promoting apoptosis of tumor cells Development and application prospect of bioactive peptides In recent years, the research of bioactive peptides with antitumor biological activity in clinical application has been widely concerned For example, thymosin has been widely used in the treatment of tumor and immune deficiency diseases (such as chronic viral hepatitis, acquired immune deficiency syndrome, etc.) The application of thymosin after radiotherapy and chemotherapy can obviously improve the immunity, reduce the infection rate and improve the quality of life Thymosin has a certain effect on the reconstruction of immune function of immunodeficient patients and the treatment of liver cancer, leukemia and other diseases Summary: tumor is a common disease, which seriously threatens human health and life However, with the development of biotechnology, more and more bioactive peptides with medical value will be found, developed and commercialized, and the development of anti-tumor peptide drugs will also make great achievements.