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    Home > Biochemistry News > Biotechnology News > What are the clinical results of the mRNA vaccine to prevent influenza Moderna?

    What are the clinical results of the mRNA vaccine to prevent influenza Moderna?

    • Last Update: 2021-12-29
    • Source: Internet
    • Author: User
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    On December 10, 2021, Moderna announced that its Phase 1 clinical trial of the influenza vaccine mRNA-1010 has obtained positive interim data


    The epidemic of seasonal flu causes respiratory diseases and places a huge burden on the healthcare system


    However, the current influenza vaccines are only about 40-60% effective, and their formulations were decided 6-9 months before the planned use of the vaccine


    This phase 1 clinical trial evaluated the effects of 3 doses of mRNA-1010 (50 µg, 100 µg, and 200 µg) in a cohort of young adults (18-49 years) and elderly (over 50 years)


    ▲The immunogenicity data of mRNA-1010 in young adults (picture source: Moderna official website)

    In the elderly group, compared with baseline, the increase in antibody GMT was 6 times (H1N1), 6 times (H3N2), 3 times (Yamagata), and 2 times (Victoria)


    In terms of safety, no serious safety signals were observed


    Mr.


    Reference materials:

    [1] Moderna Announces Positive Interim Phase 1 Data for mRNA Flu Vaccine and Provides Program Update.


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