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    Home > Active Ingredient News > Antitumor Therapy > WCLC 2022|Can sintilimab combined with short-course chemotherapy regimens promote strengths and avoid weaknesses?

    WCLC 2022|Can sintilimab combined with short-course chemotherapy regimens promote strengths and avoid weaknesses?

    • Last Update: 2022-08-20
    • Source: Internet
    • Author: User
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    foreword

    The 2022 International Association for the Study of Lung Cancer (IASLC) World Conference on Lung Cancer (WCLC) will be held in offline + online format from August 6 to 9, 2022



    Research Introduction

    Most advanced sq-NSCLC patients are older, have a history of heavy smoking, and have multiple comorbidities, and are considered to be poorly tolerant to chemotherapy


    Research methods

    Eligible patients received sintilimab (200 mg, IV) in combination with nab-paclitaxel and carboplatin (D1, Q3W) for 2 cycles


    Research result

    A total of 44 patients were enrolled for treatment from May 2020 to February 2022



    Figure 1 PFS


    At data cutoff, 36 patients (81.



    Table 1 Adverse events


    Analysis conclusion

    As a first-line treatment for advanced sq-NSCLC, sintilimab combined with two cycles of nab-paclitaxel/carboplatin showed encouraging PFS and manageable safety profile



    references:

    EP08.



    Editor: Jiang Zhou Typesetting: Jiang Zhou Execution: Uni
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