Warning words for poisonous traditional Chinese Medicine

Recently, the State Food and Drug Administration issued a notice, requiring the specification of Chinese patent medicines containing toxic Chinese herbal pieces to add warning words, including the varieties of Chinese patent medicines involving state secret technology Experts pointed out that, on the one hand, this change is an important step in the scientific and standardized management of traditional Chinese medicine, in order to calm the misunderstanding of the international community on the toxic Chinese patent medicine in China Xia Wen, a reporter from Beijing times, 28 kinds of poisonous Chinese herbal medicines should be warned that traditional Chinese medicine is covered with a mysterious veil in the eyes of many people Every time when a formula is announced, some pharmaceutical companies jump out and refuse to disclose it on the grounds of ancestral secret recipe and secret formula Now, the veil is expected to be lifted The notice of the general office of the food and Drug Administration on the revision of the specifications of Chinese patent medicines containing toxic Chinese Herbal Pieces clearly points out that where the prescriptions contain the varieties of Chinese patent medicines (processed products containing toxic drugs) made of 28 kinds of toxic Chinese herbal medicines collected in the measures for the Administration of toxic drugs for medical use, the relevant drug manufacturers shall indicate the varieties of Chinese patent medicines in their specifications (ingredients) Name of toxic Chinese herbal pieces, and add warning words: "this product contains ××" In particular, it is mentioned that the specifications of Chinese patent medicines involving state secret technology shall be revised in accordance with the above requirements According to the regulations, relevant drug manufacturers need to apply for filing before December 31 of this year The reporter learned that 28 kinds of toxic traditional Chinese medicine ingredients required to be noted by the State Food and drug administration included arsenolite (red arsenic, white arsenic), arsenic, mercury, raw horse front son, raw Sichuan black, raw grass black, raw white aconite, raw aconite, raw pinellia, raw Nanxing, raw Croton, cantharides, green Niang, red Niang worm, raw kansui, raw wolfram, raw rattan yellow, raw gold, raw celestial fairy , naoyanghua, Yizhihao on snow, hongshengdan, baijiangdan, toad cake, Yangjinhua, Hongfen, Qingfen, realgar These ingredients of traditional Chinese medicine may sound strange at first, but many of the medicines containing these ingredients are the regular medicines of many families Reporters visited Jinxiang pharmacy and baishide pharmacy and found that Tongrentang Huoxiang Zhengqi water and Tianshi rehabilitation prescription fresh bamboo juice contain "Sheng Banxia", Yunnan Baiyao Shangshi Zhitong paste, Tianhe Shexiang Zhuanggu paste and Tongrentang Goupi paste contain "Sheng Chuanwu"; Tongrentang papaya pill, huoluodan and yangantang Sanqi injury pill contain "Sheng Caohu"; Tongrentang Jinkui Shenqi Pill, Zhongjing Yougui Pill Fuzi Lizhong tablet contains "shengfuzi"; Tongrentang Niuhuang Jiedu pill, Angongniuhuang pill and Niuhuang Jiedu soft capsule contain realgar Xu Ming, pharmacist in the pharmacy department of the First Affiliated Hospital of Tsinghua University, told reporters that most of the above traditional Chinese medicine is used to treat rheumatism, joint pain or malignant tumors "Most of these traditional Chinese medicines are highly toxic, such as arsenic and Pinellia ternate, which belong to the category of" big poison " However, as long as they are scientifically combined, scientifically processed and strictly dosed, and the doctor's careful prescription, the use of these traditional Chinese medicines should be safe." Sun Zhongshi, an expert of the national monitoring system for rational use of drugs of the health and Family Planning Commission, told reporters that the move is a good thing for the pharmaceutical industry and a major measure for the scientific and standardized management of the use of traditional Chinese medicine He pointed out that if traditional Chinese medicine wants to go abroad, it must act in accordance with the international rules, "it is against this background that the State Food and Drug Administration issued this initiative." In 2013, many well-known pharmaceutical enterprises were shot in succession because of the production of Chinese patent medicine containing toxic decoction pieces but did not tell the ingredients of the toxic decoction pieces Many Chinese patent medicine products have been questioned in the domestic and international markets At the beginning of this year, the relevant departments of Hong Kong and Macao ordered the recovery of five categories of Yunnan Baiyao products in the market, including "Yunnan Baiyao capsule", "Yunnan Baiyao Powder", "Yunnan Baiyao cream", "Yunnan Baiyao aerosol" and "Yunnan Baiyao tincture", and called on the people to stop using them The reason is that the Hong Kong government laboratory found that the samples of Chinese patent medicines related to these five products contain unidentified aconitine alkaloids And Tongrentang's "five tonic pills for health" were also detected by the Hong Kong Department of health that the mercury (mercury) content exceeded the standard In addition, the international market of traditional Chinese medicine is also very bumpy this year At the beginning of this year, the Health Ministry of Canada issued a circular warning the public not to buy and take a number of Chinese patent medicines containing excessive heavy metals such as mercury and lead, including Tianma headache pill, Dendrobium night light pill, neizhangmingyan pill, Tianma pill and Baifeng pill On August 20, the UK Drug Administration issued a warning on its website, reminding people to be cautious about choosing some traditional Chinese medicines that have not been officially registered in the UK, saying they contain high levels of harmful toxins, including lead, mercury and arsenic The products warned include Niuhuang Jiedu tablet of Tongrentang, Baifeng pill of baolingtang and Fabao of henglongchang Sun Zhongshi pointed out that traditional Chinese medicine has always been managed by the state according to traditional methods Unlike western medicine, traditional Chinese medicine has undergone strict evidence-based medicine demonstration, so it is difficult to be recognized by the international market He stressed that the action of the State Food and drug administration, to a certain extent, broke the "mystification" of traditional Chinese medicine "In the past, some pharmaceutical companies always talked about the ancestral secret recipe and secret formula, and consumers were kept in the dark Labeling toxic traditional Chinese medicine ingredients, making information more transparent, helps consumers to choose rationally " Adverse reactions "not clear" is expected to improve the requirements of the State Food and drug administration Pharmaceutical enterprises should actively track the safety of clinical application of drugs, and timely supplement and improve the safety content such as instructions (precautions) according to the adverse reaction monitoring data and relevant safety information reported in the literature Ms Ma, the consumer, told the reporter that she would read the drug manual before taking medicine every time However, whether the manual of traditional Chinese medicine is "adverse reaction" or "use taboo", there are usually only four simple words "not clear yet" "To be honest, because I haven't made these four words clear, I'm afraid every time I use Chinese patent medicine for my children." The reporter inquired about 10 kinds of Chinese patent medicines, and found that none of them had clear adverse reactions and taboos "Fufang Houttuynia granules" in Bangqi pharmaceutical industry, "Jianwei Xiaoshi tablets" in Jiangzhong pharmaceutical industry, "Banlangen Granules" in Baiyunshan Pharmaceutical industry, "Huaning effervescent tablets" in Shenge pharmaceutical industry, "Xiaoer Hulu powder" in daningtang pharmaceutical industry, "Linghuang Baoer pill" in jingxiutang pharmaceutical industry, "Xiaoer Shuangqing granules" in Nuodikang pharmaceutical industry, "Xiaoer hot speed Qingkou medicine" in Yizheng pharmaceutical industry, "Shandong Jianmin Pharmaceutical Industry" "Infant Jianpi powder" and "xuanmaiganju granules" of Taiji pharmaceutical industry are not clear about the adverse reactions and taboos In an interview with the media, Ji Shaoliang, a professor at Beijing University of traditional Chinese medicine, pointed out that many of the adverse reactions in the instructions of Western medicine are long and long, while traditional Chinese medicine often marked "unclear" "They are desperately searching, we are desperately concealing." Sun also reminded that the "unclear" side effect of traditional Chinese medicine does not mean that it has no side effect In fact, there are many cases of serious adverse reactions of traditional Chinese medicine in recent years He pointed out that the industry of traditional Chinese medicine should attach great importance to adverse drug reactions, because finding and fully explaining adverse drug reactions as much as possible can help patients to use drugs safely After the State Food and Drug Administration issued the new measure, it soon issued a notice requiring the modification of the instructions of Xiaoyan Lidan tablets According to the public information, Xiaoyan Lidan tablet is a kind of heat clearing, dampness removing and choleretic medicine Its main ingredients are Andrographis paniculata, Xihuangcao and Kumu Although "bitter wood" is not among the 28 kinds of poisonous medicinal materials listed by the state, the State Food and drug administration requires that the content of bitter wood contained in this product should be added to the drug precautions, which is not suitable for taking for a long time At the same time, the adverse reactions including nausea, vomiting and abdominal pain were added.