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USTC reveals the heterogeneity of resident NK cells in the liver

 Last Update: 2022-05-10
 Source: Internet
 Author: User

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On May 2, 2022, the team of Professor Tian Zhigang and Professor Peng Hui from the University of Science and Technology of China published a paper entitled "Ly49E separates liver ILC1s into embryo-derived and postnatal subsets with different functions" in the internationally renowned journal "Journal of Experimental Medicine".

As an important member of innate immunity, NK cells (natural killer cells, natural killer cells) are abundant in the liver

Through single-cell sequencing technology and flow cytometry analysis, the research group found that liver ILC1s can be divided into two groups of cells , Ly49E + and Ly49E- .

Figure 1 Subpopulation composition map of liver NK cells (Group 1 ILCs)

The research work was supported by the National Natural Science Foundation of China, the Ministry of Science and Technology, and the Chinese Academy of Medical Sciences

Paper link: https://doi.

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