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Uses and applications of Soluplus in pharmaceutical preparations

 Last Update: 2022-10-02
 Source: Internet
 Author: User

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pharmaceutical

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Soluplus is a new type of amphiphilic non-ionic pharmaceutical polymer material with a glass conversion temperature (Tg) of Soluplus (polyethylene caprolactam-polyvinyl acetate-polyethylene glycol grafting copolymer) in pharmaceutical preparations, with high safety, solubilization, crystalline suppression, spatial stability, suspension, heat sensitivity, film formation, etc.
, and has shown good application prospects in improving the dissolution rate and bioavailability of insoluble drugs.
This paper reviews the application progress of Soluplus in solid dispersions, polymer micelles, drug nanocrystals, supersaturated autoemulsification delivery systems, etc.
, and also points out that Soluplus has limited
scope due to low Tg value and strong hydrophilicity.

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