-
Categories
-
Pharmaceutical Intermediates
-
Active Pharmaceutical Ingredients
-
Food Additives
- Industrial Coatings
- Agrochemicals
- Dyes and Pigments
- Surfactant
- Flavors and Fragrances
- Chemical Reagents
- Catalyst and Auxiliary
- Natural Products
- Inorganic Chemistry
-
Organic Chemistry
-
Biochemical Engineering
- Analytical Chemistry
-
Cosmetic Ingredient
- Water Treatment Chemical
-
Pharmaceutical Intermediates
Promotion
ECHEMI Mall
Wholesale
Weekly Price
Exhibition
News
-
Trade Service
Re-epithelialization is defined as the reconstitution of cells into an organized, stratified squamous epithelium that permanently covers a wound defect and restores function (
1
). Following wounding, keratinocytes are activated to undergo a series of phenotypic changes that have been well-characterized in vivo (
2
–
4
). However, in vitro studies of re-epithelialization have often been limited by their inability to simulate the in vivo tissue. Wound models using skin explants (
5
–
8
) or submerged keratinocyte cultures (
9
,
10
) demonstrate only partial differentiation and hyperproliferative growth. These systems have been useful for studying keratinoctye migration (
11
), but are limited in studying other aspects of re-epithelialization.
