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Universal CAR-NK for relapsed/refractory B-cell lymphoma, 3/6 cases achieved CR

 Last Update: 2022-05-25
 Source: Internet
 Author: User

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On April 25, U.

NKX019 is a CD19-targeting CAR-NK cell therapy from Nkarta and a "universal" CAR-NK cell therapy

Lymphoma leukemia high-dose (10x10 ⁸ CAR-NK cells, 3 infusions) group, of 6 evaluable patients: 5 achieved objective response (ORR=83%), 3 achieved complete response (CR=50%) , including one patient with diffuse large B-cell lymphoma and one patient with mantle cell tumor

Likewise, no dose-limiting toxicities, as well as adverse events similar to the side effects of CAR-T

CAR-T

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