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UK NICE attitude U-shaped reversal: support Johnson & Johnson Erleada in the treatment of two types of prostate cancer patients

 Last Update: 2021-09-20
 Source: Internet
 Author: User

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After being rejected by the National Institute of Health and Care Excellence (NICE), Johnson & Johnson’s Erleada drug has recently regained NICE’s positive opinion.

In May 2021, NICE issued a draft guideline.

The current standard treatment for hormone-relapsed non-metastatic prostate cancer is ADT alone or together with darolutamide (another androgen receptor inhibitor)

At the time, NICE attributed this uncertainty to the special circumstances of the patients in the trial

NICE said in a statement that it will use a clinical framework based on personal risk to identify patients who are not suitable and cannot tolerate docetaxel

As a follow-up product of Johnson & Johnson's prostate treatment Zytiga, Erleada is a new type of non-steroidal androgen receptor (AR) inhibitor, which can block the action of androgens, thereby inhibiting tumor growth

A series of successful regulatory results for the drug are supported by data from Phase III trials

In China, Erleada also received accelerated approval in September 2019 for the treatment of adult patients with nmCRPC who are at high risk of metastasis.

Reference source:

2.
Another discount does the trick: Johnson & Johnson wins NICE backing for prostate cancer drug Erleada

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