Type O blood wins! The latest research has found that blood type can predict the risk of stroke before the age of 60, and blood type O has the lowest risk!

Stroke, also known as "stroke," is reported to kill an average of one Chinese every 16 seconds
.
A stroke is a specific event
that damages the brain or causes the death of brain tissue.
The most common type of stroke is ischemic stroke
.
An ischemic stroke
occurs when something, such as a blood clot, blocks the blood supply to the brain.
Without an adequate blood supply, the brain cannot get the oxygen it needs, and brain cells die
due to lack of oxygen.

The brain controls the rest of the body, so damage to it can lead to long-term consequences
.
Thus, identifying risk factors for stroke can help raise awareness and hopefully prevent stroke
.

Recently, the results of a new meta-analysis led by researchers at the University of Maryland School of Medicine (UMSOM) showed that a person's blood type may be related to their risk of early stroke, with people with blood type A having the highest risk of stroke before age 60, and people with blood type O having the lowest
risk of stroke.
The findings were published in the journal Neurology
.
The meta-analysis included all available data from genetic studies, focusing on ischemic strokes caused by obstruction of blood flow to the brain, occurring in
young people under 60 years of age.

Steven J.
Kittner, a neurologist at the University of Maryland Medical Center, said, "The number of early strokes is on the rise
.
These people are more likely to die from life-threatening events, and survivors may face decades of disability
.
Still, there is little
research on the causes of early stroke.
”

He and his colleagues conducted a meta-analysis of 48 studies on genetic and ischemic stroke, including 16,730 stroke cases and 599,237 healthy controls
who had never experienced a stroke.
They then looked at all the collected chromosomes to identify genetic variants associated with stroke and found a link between early-onset stroke, which occurs before age 60, and chromosomal regions that include blood types that determine whether blood types are A, AB, B, and O
.

In this study, the researchers divided participants by blood type and compared them to stroke status: early stroke, late stroke, and no stroke
.
The results found:

1.
People who have had an early stroke are more likely to have blood type A and less
likely to have blood type O than people who have had a stroke or have not had a stroke later in life.

2.
People with early and late strokes are more likely to have type B blood
than controls.

After adjusting for gender and other factors, the researchers found:

1.
People with blood type A have an 18%
higher risk of early stroke than people with different blood types.

2.
People with blood type O have a 12%
lower chance of early stroke than people with other blood types.

Study co-author and principal investigator Braxton D.
Mitchell said: "Our meta-analysis looked at people's genetic profiles and found an association
between blood type and early-onset stroke risk.
The association between blood type and late-onset stroke is much
weaker than the early-onset stroke we found.
”

The researchers emphasize that the increased risk of stroke is very mild and that people with blood type A should not worry about early-onset stroke or additional screening or medical testing
based on this finding.

In addition, the researchers add, "We still don't know why blood type A carries a higher risk, but it may be involved in clotting factors such as platelets and vascular endothelial cells, as well as other circulating proteins, all of which play a role
in thrombosis.
" Previous studies have shown that people with type A blood have a slightly higher risk of developing blood clots in their legs, called deep vein thrombosis
.
We clearly need more follow-up research to elucidate the mechanisms
by which stroke risk increases.
”

The study also has certain limitations:

1.
The study mainly includes participants
of European ancestry.
About 35% of participants were of non-European ancestry
.
This means that more diverse follow-up actions
are needed.

2.
The study was also unable to determine the cause of this link between blood type and stroke, so further data collection could focus on
causal factors rather than associations.

3.
Limited sample size limits researchers' ability to
see unique subtypes and more detailed factors.

In any case, this study tells everyone that many people may experience a stroke, and the introduction of this conclusion should change the risk factors for stroke
.
While people can't change their blood type, people can control other stroke risk factors to help reduce risk
.
For example, high blood pressure, diabetes, high cholesterol levels, smoking, and obesity are all risk factors
for stroke.
People can take steps to change these risk factors, for example, people can follow healthy dietary advice and exercise regularly, stay in close contact with doctors and other medical professionals to push themselves towards a healthy lifestyle and address underlying health issues
.

References:

https://n.
neurology.
org/content/early/2022/08/31/WNL.
0000000000201006