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Twist Bioscience today announced the launch of the Twist 96-Plex Library Prep Kit, an efficient and economical next-generation sequencing (NGS) prep kit
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Recently, new approaches to sequencing-based genotyping (GBS) have unlocked the potential of NGS to not only improve data quality and yield, but also significantly improve laboratory processes and reduce sample preparation costs
Matt Huentelman, associate professor of neurogenomics at the Translational Genomics Institute (TGen), said: "Using the 96-plex library prep kit, we were able to identify a statistically significant inheritance in Westie lung disease that was previously missed by microarray technology.
Association.
Westie lung disease is a canine model of human idiopathic pulmonary fibrosis (IPF)
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Sri Kosuri, founder and CEO of Octant, commented: "We need a reliable, scalable, and low-touch method to verify complete plasmid sequences.
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From a time and cost perspective, library preparation is a major bottleneck in the sequencing pipeline
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By pre-multiplexing up to 960 samples, combined with best-in-class enzymes and optimized oligonucleotide and buffer conditions, the Twist 96-plex library prep kit (formerly iGenomX's RIPTIDE) saves time in late-stage reactions required reagent volume and reduce manual processing time per sample
"The genotyping enabled by the 96-plex library prep kit is a major advance over microarrays," said Associate Professor Ali Torkamani, Director of Genomics and Genome Informatics at the Scripps Translational Research Institute, part of the Scripps Research Institute
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This approach provides markers across the genome at higher densities and at significantly lower cost
Dr.
Emily M.
Leproust, CEO and Co-Founder of Twist Bioscience, said: "The Twist 96-plex Library Prep Kit includes a robust PCR-like workflow for ultra-high-throughput library construction, allowing customers to utilize low-volume sequencing data to complete high-quality genotyping across the entire genome
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Following the acquisition of iGenomX, we 'Twistified' the product, which we believe will help customers conduct studies with hundreds to thousands of samples, whether Screening the traits of seeds is also to verify the sequence of plasmid colonies
About Twist Bioscience
Twist Bioscience is a leading and fast-growing synthetic biology and genomics company developing disruptive DNA synthesis platforms to advance the industrialization of bioengineering
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The platform's core patented technology enables a new way of making synthetic DNA by "writing" DNA on a silicon chip
Legal Notice Regarding Forward-Looking Statements
This press release contains forward-looking statements
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All statements other than historical facts, including, but not limited to, expected cost savings resulting from the use of the Twist 96 Multiplex Library Prep Kit, are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995 and are a reflection of management Forward-looking statements of current beliefs and expectations
