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    Home > Active Ingredient News > Endocrine System > Trying to lose weight but always failing? It may be that your intestinal flora is "to blame"!

    Trying to lose weight but always failing? It may be that your intestinal flora is "to blame"!

    • Last Update: 2022-11-05
    • Source: Internet
    • Author: User
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    *Only for medical professionals to read and refer to regulating the intestinal flora can also be regarded as a non-dieting weight loss methodMany

    obese people have tried dieting, exercise, diet pills and


    other methods
    in order to lose weight.
    Some people do succeed, while most people continue to develop
    in the direction of obesity.

    Why do some people successfully lose weight, while others gain weight after drinking three meals? It may have something to do with your gut flora!


    Regulating the gut flora may be more important than you think!


    The intestinal flora is known as a "stealth organ" that carries the "second gene" of the human body, and is even considered an endocrine organ
    .
    Tens of thousands of microorganisms live in the human intestine, forming the intestinal flora, such as bifidobacteria, lactobacilli, etc.
    , which
    help the body digest indigestible food
    .
    It can also participate in the metabolism of sugars and proteins, while promoting the absorption of iron, magnesium, zinc and other mineral elements, regulating the body's hunger signals, affecting people's appetite and satiety
    .



    Studies have shown that the gut microbiota can affect the expression of genes involved in fat synthesis, namely adipocytokines, also known as FIAF factors
    .
    This gene helps reduce fat accumulation and promotes fat consumption
    .
    In normal-weight people, the FIAF gene is turned off when not hungry, and works while starving, providing energy
    to the body by consuming the body's stored fat.
    In obese patients, the FIAF gene is turned off for a long time, unable to effectively consume fat, and also promotes the
    body's fat synthesis.



    What hinders your weight loss may be "fat bacteria"

    In one trial, researchers helped a young man weighing 175 kilograms lose 51.
    4 kilograms
    in 23 weeks.
    How is this done?


    The research team first discovered Enterobacter cloaca b29 (which accounts for 35% of the total intestinal flora) in this person, and then began nutritional interventions
    .
    After 4 weeks, it was found that this bacterium was basically undetectable, and finally successfully achieved weight
    loss.


    With weight loss, the patient's diabetes, hyperlipidemia, and hypertension also returned to the normal range
    .
    Then the research team transplanted the bacteria into the intestines of other volunteers, and found that the originally thin people also began to gain weight
    rapidly.


    Many people always encounter a problem when losing weight, that is, after losing weight, the weight will rise rapidly, and recurrent obesity will occur, which may also be related
    to the intestinal flora.
    That is, the intestinal flora has a memory, and it may quickly return to its original state after you lose weight, and your body will return to its original shape with it
    .
    Therefore, if you want to lose weight without rebounding, you should also pay attention to
    adjusting the intestinal flora~


    Still others are obese due to lifestyle influences
    .
    The intestinal flora fluctuates in a 24-hour rhythm, and the host's lifestyle is reversed day and night, which will
    have a certain impact on metabolism and make "fat bacteria" want to move
    .
    That is, lack of sleep may lead to obesity
    by altering the intestinal flora.


    If we want the intestinal flora to "get along" with us, we must pay attention to proper stress relief, maintain adequate sleep, have a reasonable diet, etc.
    , which help adjust the intestinal flora
    .
    Of course, this is a long-term process, but considering the ultimate benefits, it is worth a try!
    Audit expert
    Li Jia



    • Director of the Department of Endocrinology, Southern Theater General Hospital, medical doctor, graduate supervisor
    • Vice Chairman of Clinical Endocrine Drug Evaluation Branch of China Medical Education Association
    • Chairman of the Osteoporosis Prevention and Rehabilitation Committee of Guangdong Geriatric Health Association
    • Youth Committee Member of Endocrinology Branch of Guangdong Medical Association
    • Vice Chairman of Diabetes Branch of Guangzhou Medical Association
    • He has published more than 40 papers in SCI and core journals
    • He is the chief editor, co-editor and translator of 5 monographs
    • In recent years, he has presided over 5 national nature, provincial and ministerial funds
    • He has served as a simultaneous interpreter for the conference for many times
    • Reviewer for several SCI journals

    References: [1] Liu Jianing and Li Li, "Weight loss has been repeatedly defeated, it may be too many "fat bacteria"[J].
    Public Health, 2021.
    8

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