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The gut microbiota (GM) metabolites can regulate the physiological functions of the host brain through the gut-brain axis.
Adopt a diet with increased sugar and fat content (high-sugar and high-fat (HSHF) diet) to interfere with host GM.
In mice fed a high-sugar and high-fat diet for 4 months, bacterial imbalance affected the homeostasis of the intestinal tract.
In mice fed a high-sugar and high-fat diet for 4 months, bacterial imbalance affected the homeostasis of the intestinal tract.
In mice fed a high-sugar and high-fat diet for 4 months, bacterial imbalance affects the pathology of brain tissue.
In mice fed a high-sugar and high-fat diet for 4 months, bacterial imbalance affects the pathology of brain tissue.
In mice fed a high-sugar and high-fat diet for 4 months, bacterial disorders affected brain function and circRNA sequencing.
In mice fed a high-sugar and high-fat diet for 4 months, bacterial disorders affected brain function and circRNA sequencing.
In mice fed a high-sugar and high-fat diet for 4 months, bacterial imbalance affects neurotransmitter metabolism by targeting the gut-brain axis.
In mice fed a high-sugar and high-fat diet for 4 months, bacterial imbalance affects neurotransmitter metabolism by targeting the gut-brain axis.
In mice fed a high-sugar and high-fat diet for 4 months, bacterial imbalance affects neurotransmitter metabolism by targeting the gut-brain axis.
In mice fed a high-sugar and high-fat diet for 4 months, bacterial imbalance affects neurotransmitter metabolism by targeting the gut-brain axis.
The study proved that the dysbiosis induced by the consumption of HSHF diet destroys the intestinal tract and changes the neurotransmitter metabolism in the intestine and brain.
The dysbiosis induced by the consumption of HSHF diet destroys the intestines and changes the neurotransmitter metabolism in the intestines and brain.
Guo, Y.
Guo, Y.
, Zhu, X.
, Zeng, M.
et al.
A diet high in sugar and fat influences neurotransmitter metabolism and then affects brain function by altering the gut microbiota.
Transl Psychiatry 11, 328 (2021).
https:/ /doi.
org/10.
1038/s41398-021-01443-2 Guo, Y.
, Zhu, X.
, Zeng, M.
et al.
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