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Since being named Technology of the Year by Nature Methods in 2020, space biology is becoming the mainstream technology of genome science
When carrying out transcriptome analysis, the maintenance of the spatial background is essential for understanding key information such as cell biology, developmental biology, neurobiology, and tumor biology
The GEN website recently listed the world's top ten companies in the field of space biology, including five listed companies and five private companies
Top 5 listed companies
1.
Bruker has established a number of space biology positions in the past year
2.
10x Genomics maintained a strong growth momentum in the second quarter of this year, with revenue nearly doubling year-on-year to reach 116 million U.
3.
Fluidigm's basic business rebounded in the second quarter, mainly driven by the new fourth-generation CyTOF® XT™ mass spectrometry flow system
4.
NanoString Technologies achieved a milestone in the second quarter: global sales of nCounter instruments reached 1,000 units
5.
Japan's Akoya Biosciences went public in April and raised US$138.
Top 5 private companies
1.
Ultivue is committed to advancing the development of precision medicine solutions through the exploration and verification of biomarkers, and has developed a unique analysis method for multiple immunofluorescence imaging and analysis
2.
RareCyte's Precision Biology™ solution enables customers in oncology and disease research to perform multiple analyses of cells and tissues, thereby bringing new treatment methods and diagnostic tests to the market
.
In June, RareCyte launched a liquid biopsy analysis that can help customers evaluate the expression of neuroendocrine marker synaptophysin (SYP) on tumor circulating cells
.
3.
Total
funds raised by Vizgen : US$51 million
Vizgen's MERSCOPE platform is based on the famous MERFISH technology (multiple error-resistant fluorescence in situ hybridization, developed by Dr.
Xiaowei Zhuang), which aims to achieve highly multiplexed, genome-scale nucleic acid imaging with a resolution as low as 100 nm and can capture entire slices Go to single-cell and sub-cell detail data
.
MERSCOPE can help researchers to carry out organization-scale basic research and translational research, which is suitable for oncology, immunology, neuroscience, infectious diseases, developmental biology, cell therapy, gene therapy and other fields
.
4.
Lunaphore Technologies
total funds raised: 38.
3 million Swiss francs (approximately 42.
3 million US dollars)
The goal of Lunaphore Technologies is to bring space technology into mainstream laboratories that study cancer and other diseases
.
Last month, the Swiss space biology company established a partnership with the Institute of Pathology at the University of Bern
.
Researchers will use Lunaphore's COMET™ highly multiple immunostaining technology to study the tumor buds of colorectal cancer, thereby improving cancer prognosis and personalized treatment
.
5.
Resolve Biosciences and Rebus Biosystems (tied)
raised a total of 21.
5 million euros and 26.
5 million US dollars, respectively
Resolve Biosciences compares its spatial methods to mapping, and its platform Molecular Cartography™ aims to help scientists solve complex biological challenges in the fields of oncology, neuroscience, and infectious diseases
.
Rebus Biosystems uses its patented Synthetic Aperture Optics (SAO) technology to launch the Rebus Esper spaceomics platform
.
SAO is an ultra-high resolution technology that can quantitatively analyze tens of millions of cell characteristics among hundreds of thousands of cells
.
Rising star
▪ Advanced Cell Diagnostics (ACD, acquired by Bio-Techne)
▪ Dovetail Genomics
▪ Ionpath
▪ Single Technologies
▪ Singular Genomics
▪ S2 Genomics
▪ Veranome Biosystems
▪ Visikol (acquired by CELLINK)