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Today, the top academic journal "Cell" published an interesting paper online
The press release corresponding to the study states that the gut performs several seemingly contradictory functions at the same time—on the one hand, they need to absorb water and nutrients from the external environment; Microbes invade the blood and cause infection
In mouse models, the scientists mapped different fungi in the gut and found that certain fungi always accumulated near specific intestinal epithelial cells, suggesting that they may have close contact with surrounding epithelial cells
Interestingly, these fungi appear to do more than maintain barrier function in the gut
In order to find the distance behind, the researchers further explored and found that the key lies in a type of T cells
To verify this finding, the scientists performed another experiment
▲ Illustration of this study (Image source: Reference [1])
Prof.
Regarding the study, Professor Iliev commented that "it is a harmony, a communication that spans two different species"
References:
[1] Irina Leonardi et al.
[2] Preclinical study finds gut fungi influence neuroimmunity and behavior, Retrieved February 16, 2022, from https:// abridged)