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The COVID-19 pandemic has not yet faded, and the monkeypox virus has followed
At present, the widely commercialized CRISPR nucleic acid detection test strips on the market can only display the cutting products of a single reporter molecule, so although a large number of heavy-level research results have been formed in the field of scientific research, it is still difficult to meet the IVD industry's demand for double-target positive detection of the same sample, so it has not been widely used
Tiosbio focused on the "technological innovation + advanced manufacturing" of in vitro diagnostic nucleic acid detection test strip products, and launched two new dual-target nucleic acid detection test strips based on CRISPR Cas:
1.
JY0307 is suitable for RAPID DETECTION kits for IVD pathogens
When the CRISPR signal probe (detection line T1) and the double-stranded amplification product (detection line T2) are modified as follows, JY0307 can be used for detection - the CRISPR signal probe is modified with biotin (Biotin) at one end and the isothiocyanate luciferin (FITC) or 6-carboxyfluorescein (6-FAM) at the other end; One end of the amplification product is modified with digoxin (Dig) and the other end is modified with rhodamine (TAMRA
The meaning of the color rendering results of the different detection lines and quality control lines of JY0307 is shown in the following figure
2.
JY0308 is suitable for double-stranded product detection after Cas12 and Cas13 double digestion
What makes JY0308 special is that the product is a color-changing double-correction color-rendering test strip
The meaning of the color rendering results of the different detection lines and quality control lines of JY0308 is shown in the following figure
Beijing Baoying Tonghui Biotechnology Co.
Technical support WeChat ID: 13126616699