Three reasons lead to less and less "exclusive drugs"?

June 25, 2013 source: Changsha Evening News "came to buy Dieda Jieyu tablet, but was told to stop production." Yesterday, Mr Hu, who was on a business trip from Changde to Changsha, came to Hunan Provincial Hospital of traditional Chinese medicine and wanted to buy a kind of self-made medicine that his father had been thinking about, but he fell into a void From more than a thousand species to 549 now Why are there less and less self-made drugs in Changsha hospital which have been praised and praised by patients? In recent days, the reporter has conducted in-depth interviews and invited relevant experts to "feel the pulse" for this situation Experts believe that the increase of audit standards, the increase of cost and the limitation of R & D ability are the three main reasons for the sharp decrease of self-made drugs in recent years In the early stage, especially before the 1990s, the development level of China's pharmaceutical industry is generally low, and there are some difficulties in drug supply The existence of hospital self-made preparations has largely alleviated these difficulties With the development of the pharmaceutical industry, large-scale production has been realized, such as large-scale infusion, and hospital self-made agents have been gradually reduced " According to Li Hui, director of the safety supervision department of Changsha food and drug administration, the drug supervision department now stipulates that hospital self-made drugs can only involve drug varieties that are not supplied in the market In addition, the drug supervision department has also increased the supervision of hospital self-made drugs and raised the threshold of self-made drug audit, which has led to the decrease of hospital self-made drugs year by year According to Li Hui, at present, the hospital's self-made drugs need to pass the "four passes" when they are put on the market: the preparation room must have the corresponding qualification and obtain the preparation production license; all raw materials of the self-made drugs must pass the inspection; the whole production process of the preparations needs to be submitted to the Drug Administration for approval and obtain the license approval document number before they can be produced; the self-made drugs need to pass the inspection of the drug administration In addition, the hospital preparation room also needs to be regularly accepted If it fails, the hospital preparation room will face closure or partial shutdown "At present, the varieties of self-made drugs that have been greatly reduced are mainly chemical drugs, but on the whole, although the varieties of self-made drugs in hospitals are fewer, their quality has improved." Li Hui said that after the streamline of the production organization and varieties of the self-made medicine, the essence of the variety left behind is of high quality, the curative effect is more stable, and the market prospect is clearer The effect of Limited R & D capacity of medical institutions is similar to that of the decrease of self-made drugs caused by the increase of threshold The lack of R & D capacity of medical institutions is the cause of the decline of self-made drugs "As there is no preparation room, 51 kinds of self-made drugs have been unable to be produced in batches and are no longer used in the hospital since its establishment." Wang Qing, deputy director of the pharmacy department of Hunan hospital of traditional Chinese medicine, introduced that before 2001, when the hospital had its own preparation room, there were once more than 80 kinds of self-made drugs in the hospital But at the end of 2001, due to various reasons, the plan to rebuild the preparation room ran aground In the past 12 years, the self-made drugs in the hospital had shrunk to 30 There are more than one, which directly leads to the loss of many patients who trust these self-made drugs For example, rheumatism bone pain medicine wine and Dieda Jieyu tablet produced by the hospital before are all self-made drugs highly praised by patients, but after the production is stopped, this part of patients will be lost "The internal scientific research team of the hospital is not large enough, nor can it guarantee the continuity of the scientific research staff In addition, many hospitals do not have their own preparation rooms, so self-made drugs can only gradually shrink in the hospital, and it is difficult to find new students in the market." Many heads of pharmacy departments in hospitals said that the lack of investment in R & D and stamina has also become a bottleneck restricting the development of self-made drugs At present, most of the existing hospital self-made drugs are traditional Chinese medicine, but in recent years, the cost of traditional Chinese medicine has increased rapidly, but the price of drugs has not increased by an equal range, and a considerable part of drug production is unsustainable, even the more they are sold, the more they lose In the interview, the head of Pharmacy Department of many hospitals confessed that in recent years, the self-made drugs in hospitals have been shrinking or even disappearing year by year, which is closely related to the production cost On the one hand, the price of traditional Chinese medicine is rising year by year, on the other hand, it is waiting for the price department to re approve the price Before the new price comes out, the cost is borne by the hospital itself, and many hospitals have to limit the supply "Some anti-tumor drugs, animal ingredients and ore ingredients are raw materials with rapid price increase, and the common ingredients such as angelica, Astragalus and dangshen in self-made drugs are also herbs with rapid price increase In addition to the increase in the price of raw materials, the cost of self-made medicine packaging, labor costs, and even the price of labels are rising " Wang Qing introduced that, taking the self-made compound Kechuanling granules of Hunan hospital of traditional Chinese medicine as an example, the cost of each box was 56 yuan a few years ago, but now the cost of a box has exceeded 13 yuan But the price of the finished product has not increased from 1997 to 2012 Until last year, due to cost factors, the price of the self-made medicine rose from 13.6 yuan / box to 17.8 yuan / box