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Introduction: Picking your nose in any situation is not a good habit, on the one hand, it damages personal image, on the other hand, it will also cause health risks
.
Many people think they are cleaning up nasal waste, but they don't know that this behavior is very likely to increase the risk of
some diseases.
Recently, researchers from Griffith University in Australia have found that Chlamydia pneumoniae invades the central nervous system through the nasal cavity, followed by brain cells by depositing amyloid β, which is characteristic of
Alzheimer's disease.
Picking your nose regularly is likely to leave a hidden danger for bacteria to invade the central nervous system, which will increase
the risk of Alzheimer's disease.
Chlamydia pneumoniae is a respiratory pathogen that mainly infects the lungs and nasal mucosa, but can also infect the central nervous system, and its infection leads to the occurrence
of atherosclerosis, asthma, inflammatory arthritis, multiple sclerosis, delayed dementia and other diseases.
Recently, researchers have found an increasingly clear
link between Chlamydia pneumoniae infection and late-onset dementia.
Recently, researchers from Griffith University in Australia found that Chlamydia pneumoniae can infect the sense of smell, trigeminal nerve, olfactory bulb and brain of mice within 72 hours, and Chlamydia pneumoniae infection also leads to a key pathway imbalance that participates in the pathogenesis of Alzheimer's disease 7 and 28 days after inoculation, leading to β amyloid deposition
.
In addition, Chlamydia pneumoniae is able to infect peripheral nerves and central glial cells
.
That is, the nerves that extend between the nasal cavity and the brain form the pathway for Chlamydia pneumoniae to rapidly invade the central nervous system, which in turn increases the risk
of dementia by surviving glial cells and causing β amyloid deposition.
The final results were concluded with "Chlamydia pneumoniae can infect the central nervous system via the.
" olfactory and trigeminal nerves and contributes to Alzheimer's disease risk" was published in
Science Reports.
Fig.
1 Research results (Source: [1])
Whether or not Chlamydia pneumoniae is a contributing factor to neurodegeneration, it is clear that this bacterium can infect the brain and may cause chronic central nervous system lesions
.
To date, it is not clear how Chlamydia pneumoniae reaches the
central nervous system.
In this study, 1-4 months after intranasal inoculation of mice with Chlamydia pneumoniae, the researchers detected Chlamydia pneumoniae antigens and infectious microorganisms in their olfactory mucosa and olfactory bulb, and detected Chlamydia pneumoniae DNA in these tissues one week after inoculation, strongly suggesting that the bacterium can infect the central nervous system
through the olfactory nerve.
It is unclear how long after β amyloid vaccine begins to accumulate
in mice.
The nasal epithelium protects the nerves well both physically and immunologically, exhibits a strong congenital and adaptive immune system component, which, together with the lymphoid tissue associated with the nasopharynx, constitutes the body's first line
of defense against microorganisms.
But experiments have shown that nasal epithelial injury in mice increases the risk of bacterial invasion of the
olfactory nerve and bulbs.
James St.
John, one of the study authors, said: "We have found for the first time that Chlamydia pneumoniae can enter the brain directly through the nose, causing Alzheimer's disease-like diseases, which has been observed in mouse models, and this evidence is also scary for humans"
.
In addition, he suggested that if people want to reduce their risk of late-onset Alzheimer's, they need to take steps to care for their nasal passages
.
In summary, through this study, the researchers found that Chlamydia pneumoniae can rapidly invade the central nervous system of mice through the nasal cavity and lead to the deposition
of amyloid β in the central nervous system.
Picking the nose and pulling out the nose hair can damage the lining of the nasal cavity, which can cause a variety of bacteria to enter the brain, which can have various adverse consequences
.
Therefore, in order to maintain good health, you need to change your bad habit
of picking your nose and pulling out your nose hair.
.
Many people think they are cleaning up nasal waste, but they don't know that this behavior is very likely to increase the risk of
some diseases.
Recently, researchers from Griffith University in Australia have found that Chlamydia pneumoniae invades the central nervous system through the nasal cavity, followed by brain cells by depositing amyloid β, which is characteristic of
Alzheimer's disease.
Picking your nose regularly is likely to leave a hidden danger for bacteria to invade the central nervous system, which will increase
the risk of Alzheimer's disease.
Chlamydia pneumoniae is a respiratory pathogen that mainly infects the lungs and nasal mucosa, but can also infect the central nervous system, and its infection leads to the occurrence
of atherosclerosis, asthma, inflammatory arthritis, multiple sclerosis, delayed dementia and other diseases.
Recently, researchers have found an increasingly clear
link between Chlamydia pneumoniae infection and late-onset dementia.
Recently, researchers from Griffith University in Australia found that Chlamydia pneumoniae can infect the sense of smell, trigeminal nerve, olfactory bulb and brain of mice within 72 hours, and Chlamydia pneumoniae infection also leads to a key pathway imbalance that participates in the pathogenesis of Alzheimer's disease 7 and 28 days after inoculation, leading to β amyloid deposition
.
In addition, Chlamydia pneumoniae is able to infect peripheral nerves and central glial cells
.
That is, the nerves that extend between the nasal cavity and the brain form the pathway for Chlamydia pneumoniae to rapidly invade the central nervous system, which in turn increases the risk
of dementia by surviving glial cells and causing β amyloid deposition.
The final results were concluded with "Chlamydia pneumoniae can infect the central nervous system via the.
" olfactory and trigeminal nerves and contributes to Alzheimer's disease risk" was published in
Science Reports.
Fig.
1 Research results (Source: [1])
Whether or not Chlamydia pneumoniae is a contributing factor to neurodegeneration, it is clear that this bacterium can infect the brain and may cause chronic central nervous system lesions
.
To date, it is not clear how Chlamydia pneumoniae reaches the
central nervous system.
In this study, 1-4 months after intranasal inoculation of mice with Chlamydia pneumoniae, the researchers detected Chlamydia pneumoniae antigens and infectious microorganisms in their olfactory mucosa and olfactory bulb, and detected Chlamydia pneumoniae DNA in these tissues one week after inoculation, strongly suggesting that the bacterium can infect the central nervous system
through the olfactory nerve.
It is unclear how long after β amyloid vaccine begins to accumulate
in mice.
The nasal epithelium protects the nerves well both physically and immunologically, exhibits a strong congenital and adaptive immune system component, which, together with the lymphoid tissue associated with the nasopharynx, constitutes the body's first line
of defense against microorganisms.
But experiments have shown that nasal epithelial injury in mice increases the risk of bacterial invasion of the
olfactory nerve and bulbs.
James St.
John, one of the study authors, said: "We have found for the first time that Chlamydia pneumoniae can enter the brain directly through the nose, causing Alzheimer's disease-like diseases, which has been observed in mouse models, and this evidence is also scary for humans"
.
In addition, he suggested that if people want to reduce their risk of late-onset Alzheimer's, they need to take steps to care for their nasal passages
.
In summary, through this study, the researchers found that Chlamydia pneumoniae can rapidly invade the central nervous system of mice through the nasal cavity and lead to the deposition
of amyloid β in the central nervous system.
Picking the nose and pulling out the nose hair can damage the lining of the nasal cavity, which can cause a variety of bacteria to enter the brain, which can have various adverse consequences
.
Therefore, in order to maintain good health, you need to change your bad habit
of picking your nose and pulling out your nose hair.
Written by| Muzijiu
Typesetting| Muzijiu
End
Resources:
[1]Chacko A, Delbaz A, Walkden H, et al.
Chlamydia pneumoniae can infect the central nervous system via the olfactory and trigeminal nerves and contributes to Alzheimer's disease risk.
Sci Rep.
2022 Feb 17; 12(1):2759.
doi: 10.
1038/s41598-022-06749-9.
PMID: 35177758; PMCID: PMC8854390.
