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Malignant mesothelioma is a highly lethal tumor that originates mainly from the pleura and to a lesser extent from the peritoneum
.
In sporadic cases, it originates in the pericardium or the sheath of the testis
90%
Recently, a research article was published in Thorax, an authoritative journal in the field of thoracic diseases, which aimed to review the population-based incidence, treatment and survival of MPM since asbestos was banned in the Netherlands in 1993
.
The researchers included patients diagnosed with MPM or MPeM between 1993 and 2018 from the Netherlands Cancer Registry and calculated the (age-specific and sex-specific) revised annual percentage change (APC) in European normalized incidence rate (RESR)
.
In addition, we performed treatment patterns and Kaplan-Meier overall survival analyses
A total of 12,168 patients were included in the study
.
For male patients under the age of 80, the incidence of malignant mesothelioma decreased significantly over the past decade (APC between -9.
Since 2003, the use of systemic chemotherapy has increased, especially for MPM (from 9.
3% to 39.
4%)
.
Overall, 62.
It can be seen that the peak incidence of malignant mesothelioma in the Netherlands was around 2010, and the incidence of most age groups is currently declining
.
The use of systemic chemotherapy has increased since 2003, which may improve overall patient survival over time
The peak incidence of malignant mesothelioma in the Netherlands was around 2010, and the incidence is currently declining in most age groups
Original source:
Original source:Job P van Kooten, et al.
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