These two new indexes not only reflect the level of personal dietary inflammation, but also increase the risk of breast cancer by more than 150% for those with high scores?

Breast cancer (BrCa) is one of the most common cancers affecting women worldwide
.

BrCa is the leading cause of cancer death in women in developing countries and the second leading cause of death in developed countries

Breast cancer (BrCa) is one of the most common cancers affecting women worldwide

According to the existing literature, preventable risk factors related to life>
.

These factors expose individuals to systemic inflammation that destroys the immune system and leads to inflammation in the body

According to the existing literature, preventable risk factors related to life>

In this hospital-based case-control study, 253 BrCa patients and 267 non-BrCa controls were recruited
.

Food consumption was recorded to calculate the Dietary Inflammation Score DIS, the Life>

² Compared with controls, BrCa patients had significantly higher waist circumference, age at first pregnancy, history of miscarriage, number of children, and C-reactive protein (CRP), but lower intake of vitamin D supplements and anti-inflammatory drugs

The dietary intakes of the case and control participants are shown in Table 2 ​.

Although the cases had higher intakes of energy, fat, saturated fatty acids, cholesterol, carbohydrates, sodium, folic acid, and iron than controls, they had higher intakes of monounsaturated fatty acids, potassium, phosphorus, calcium, and micronutrient antioxidants such as Low in zinc, magnesium and vitamins E, C and
D.

The dietary intakes of the case and control participants are shown in Table 2 ​.

Tables 3 and 4 are the indicators of each component of the subjects in the case group and the control group, respectively
.

In terms of EDII components, higher intakes of processed meat, energy drinks, coffee, other fish, other vegetables, tomatoes, dark yellow vegetables and green leafy vegetables were observed in the cases compared to the control group lower

Tables 3 and 4 are the indicators of each component of the subjects in the case group and the control group, respectively

Breast cancer odds ratios (ORs) and 95% confidence intervals (95% CI) based on quartiles of inflammation index are shown in Table 5 ​.

Breast cancer odds ratios (ORs) and 95% confidence intervals (95% CI) based on quartiles of inflammation index are shown in Table 5 ​.

In the crude model, subjects in the highest and lowest quartiles of EDII did not show a significant risk of BrCa after adjusting for age and BMI (Model 1) .
However, when adjusted for waist circumference, energy intake, age at first pregnancy, number of children, history of miscarriage, use of anti-inflammatory drugs and vitamin D supplementation (Model 2), those in the highest quartile of EDII were significantly different from those in the lowest quartile people were more likely to have BrCa than those with digit numbers (OR: 2.
17, 95% CI: 1.
12 – 4.
22; P for trend= 0.
024) .
Breast cancer odds ratios (ORs) and 95% confidence intervals (95% CI) based on quartiles of inflammation index are shown in Table 5 ​.

In the crude model, subjects in the highest and lowest quartiles of EDII did not show a significant risk of BrCa after adjusting for age and BMI (Model 1) .
However, when adjusted for waist circumference, energy intake, age at first pregnancy, number of children, history of miscarriage, use of anti-inflammatory drugs and vitamin D supplementation (Model 2), those in the highest quartile of EDII were significantly different from those in the lowest quartile people were more likely to have BrCa than those with digit numbers (OR: 2.
17, 95% CI: 1.
12 – 4.
22; P for trend  = 0.
024) .
and trend

In the crude model, individuals in the highest DIS quartile had a higher risk of BrCa compared with the lowest quartile (OR: 2.
56, 95%CI: 1.
48 - 4.
44; P for trend < 0.
001)
.
In addition, after adjusting for confounders (Model 1 and Model 2), BrCa risk remained significant in the highest and lowest DIS quartiles (OR: 2.
67, 95%CI: 1.
53 - 4.
65; P < 0.
001, OR: 2.
13, 95%CI: 1.
15 - 3.
92; P for trend = 0.
012)
.

In the crude model, individuals in the highest DIS quartile had a higher risk of BrCa compared with the lowest quartile (OR: 2.
56, 95%CI: 1.
48 - 4.
44; P for trend < 0.
001)
.
In addition, after adjusting for confounders (Model 1 and Model 2), BrCa risk remained significant in the highest and lowest DIS quartiles (OR: 2.
67, 95%CI: 1.
53 - 4.
65; P < 0.
001, OR: 2.
13, 95%CI: 1.
15 - 3.
92; P for trend = 0.
012)
.

However, no significant association was observed between LIS and BrCa risk in either the coarse or adjusted models
.

However, no significant association was observed between LIS and BrCa risk in either the coarse or adjusted models
.

Taken together, this case-control study showed that higher EDII and DIS scores significantly increased the risk of BrCa, but there was a zero association between LIS and BrCa risk in crude and adjusted models
.
Furthermore, further analysis of the EDII and DIS indices revealed that women in the highest quartile had a higher risk of BrCa than those in the lowest quartile after adjusting for potential confounders in the fully adjusted model
.
The results of this study, as well as previous literature, suggest that diet and life>
.

This case-control study showed that higher EDII and DIS scores significantly increased BrCa risk, but there was zero association between LIS and BrCa risk in crude and adjusted models
.
Furthermore, further analysis of the EDII and DIS indices revealed that women in the highest quartile had a higher risk of BrCa than those in the lowest quartile after adjusting for potential confounders in the fully adjusted model
.
The results of this study, as well as previous literature, suggest that diet and life>
.

 

Original source:

Sohouli MH, Hadizadeh M, Mardali F, Sanati V, da Silva Magalhães EI, Zarrati M.
Association between novel dietary and life>Nutr J .
2022;21( 1): 14.
Published 2022 Mar 2.
doi: 10.
1186/s12937-022-00766-0

Sohouli MH, Hadizadeh M, Mardali F, Sanati V, da Silva Magalhães EI, Zarrati M.
Association between novel dietary and life>Nutr J .
2022;21( 1): 14.
Published 2022 Mar 2.
doi: 10.
1186/s12937-022-00766-0 Leave a message here