These clinical research results of traditional Chinese medicine have been published in the top international journals

Because traditional Chinese medicine is mostly compound preparation, evidence-based medicine research has been the short board of traditional Chinese medicine At present, evidence-based medicine research results of traditional Chinese medicine varieties have been published in the top international journals After evidence-based medicine research, its market return is also quite amazing Before evidence-based medicine research was not carried out in 2005, the annual sales of musk Baoxin Pill was only over 40 million After its evidence-based medicine research was published in the top international journals, the annual sales of musk Baoxin Pill last year has exceeded 1 billion, becoming a veritable large variety With an annual sales of 400-1.1 billion yuan, this traditional Chinese medicine has achieved good clinical effect as an effective drug for treating coronary heart disease for a long time Professor Zhang Weidong from the school of pharmacy of the Second Military Medical University led the research on this pill, which was published in science, the world's top science and technology magazine According to reports, at the beginning of research and development, the annual sales of musk Baoxin Pill was only over 40 million, and by 2014, the sales of the product had reached 1.1 billion After ten years, the annual sales volume of products has increased from 40 million to 1 billion The business operation and management of enterprises have made great contributions, but it is undeniable that the scientific research achievements have also provided a great boost to the sales growth Two R & D achievements were published in the top international journal New England Medical Journal, one in the Journal of Clinical Oncology, and two in the Journal of blood The research achievements of the team of Zhu Honghu, deputy chief physician of the Institute of Hematology, Peking University, were remarkable The team conducted evidence-based medicine research on compound Huangdai tablet After five years of clinical research, they proved that the oral preparation of compound Huangdai tablet has the same efficacy as the intravenous arsenic agent, and the cost is cheaper and more economical The research results were published in the international authoritative journal of clinical oncology and the British Journal of Hematology After that, we only used two oral drugs (compound Huangdai tablets + tretinoin) to treat acute promyelocytic leukemia without chemotherapy or infusion The research results were published in the New England Journal of medicine This study shows that the treatment of acute promyelocytic leukemia can achieve the transformation from inpatient treatment to outpatient treatment, so as to achieve lower treatment costs and higher quality of life, which fully embodies the advantages of traditional Chinese medicine treatment When communicating with cypress blue, Zhu Honghu said that there are many varieties of traditional Chinese medicine that can stand to be verified He believed that valuable varieties should first have good clinical efficacy, and indeed have effect This effect is not accidental, but can stand to be verified In evidence-based medicine research, we should follow the internationally recognized model, so that its research results can be internationally recognized Evidence based medicine research will become the foundation of the future large varieties of traditional Chinese medicine When cypress blue searches Baidu with the keywords of traditional Chinese medicine, evidence-based medicine and international journals, it finds that only a few materials are searched In 2013, the Journal of American Society of Cardiology published the research results of evidence-based medicine of Qiliqiangxin capsule in the treatment of chronic heart failure The editorial department specially commented: "make the failing heart stronger - TCM opens the door of hope for the synergistic effect of heart failure" In addition, there are also some research results For example, this year, Chongqing Institute of traditional Chinese medicine, in cooperation with Hong Kong Baptist University, recently published an article in the internationally renowned Journal oncotarget (impact factor 6.63) Halofuginone is a quinazolone compound extracted from dichroafebrifugalour, a traditional Chinese medicine After the cooperation between our hospital and Hong Kong Baptist University, we found that halofuginone can interfere with the metabolism of glucose and lipid in colon cancer cells by regulating the expression of Akt / mTORC1 signal pathway, including glycolysis and tricarboxylic acid cycle The contents of related metabolites in cyclophosphate and pentose phosphate pathway can inhibit the growth of colon cancer cells and induce apoptosis This project has important theoretical value and clinical significance for the research and development of new antitumor compounds of traditional Chinese medicine This year, the growth rate of traditional Chinese medicine is decreasing from the previous double-digit to single digit We should strictly control the auxiliary drugs, clinical pathway management, and the list of drugs reported by the hospital As a whole, the traditional Chinese medicine industry is facing great pressure It is urgent for traditional Chinese medicine enterprises to strengthen the research and development of varieties, find market growth points, and find large varieties In the past, evidence-based medicine research and clinical trials were not valued, but now, evidence-based medicine research and clinical trials of traditional Chinese medicine will become more important for the market.