These 19 autoimmune diseases are closely related to 12 cardiovascular diseases, summarized in a single table

*For medical professionals only to read and refer to young autoimmune disease patients are more susceptible to cardiovascular disease! Clinical vigilance! On August 27, 2022, the European Cardiology (ESC) Annual Conference published an article on the relationship between autoimmune diseases and cardiovascular disease in Lancet, which is based on a large cohort of 22 million people in the UK, and an analysis of the risk relationship between 19 autoimmune diseases and 12 cardiovascular diseases, shows that multiple autoimmune diseases are associated with a wide range of cardiovascular outcomes, and this association is not limited to individual specific diseases
.

Autoimmune diseases co-have a high risk of cardiovascular disease, what is the specific situation?

Using patient records from the UK Clinical Practice Research Database (CPRD), the research team collected a group of newly diagnosed patients with any of the 19 autoimmune diseases, matched them with a set of matching cohorts, followed up for several years to observe the incidence of 12 cardiovascular outcomes, and used the Cox proportional risk model to examine the differences between patients with autoimmune diseases and assess the association between the 19 most common autoimmune diseases and 12 cardiovascular diseases
。


A total of 22009375 people were included in the study, and 446449 of them were cohorts of patients with autoimmune diseases who were newly diagnosed with autoimmune disease between January 1, 2000 and December 31, 2017, and who did not have cardiovascular disease within 12 months of diagnosis; 2102830 general population was also included as a matching cohort
.

• Patients with autoimmune diseases are at increased risk of cardiovascular disease

In all subgroups, the risk of cardiovascular disease was higher in the autoimmune disease cohort than in the matching cohort
.

• The more types of autoimmune diseases, the greater the risk of cardiovascular disease

1.

• The risk of either cardiovascular disease associated with autoimmune disease is increased

The correlation between autoimmune diseases and cardiovascular disease risk is significant in any type of cardiovascular disease, with the highest
correlation in myocarditis and pericarditis, peripheral artery disease, and infective endocarditis.

• Taking targeted precautions is the next step

Nathalie Conrad, author of the paper, points out that the excess risk of autoimmune diseases in cardiovascular disease is comparable
to that of type 2 diabetes.

The results of this large, population-based cohort study support evidence from previous studies that patients with autoimmune diseases have a higher risk of cardiovascular disease than those without autoimmune disease, and that all 19 autoimmune diseases selected in the study are associated
with an increased risk of cardiovascular disease.

Because the cardiovascular system is also rich in connective tissue, autoimmune diseases often affect the cardiovascular system, and cardiovascular lesions have become one of the main causes of death of this type of
disease.

Chen Xinpeng, Deputy Chief Physician

• Shenzhen Futian Rheumatology Specialist Hospital, Director of the Department of Rheumatology of Traditional Chinese Medicine

• Visiting Scholar at Queen Mary College London, UK

• Young member of the Rheumatic Diseases Professional Committee of the Chinese Association of Integrative Traditional and Western Medicine

• He is a member of the Rheumatology Professional Committee of the Guangdong Medical Association

• Young member of the Rheumatism Professional Committee of Guangdong Association of Integrative Traditional Chinese and Western Medicine

• Expert of Shenzhen Health Education Science Popularization Expert Group

• Vice President of Rheumatology Immunologist Branch of Shenzhen Medical Doctor Association

• Member of the Standing Committee of the Rheumatology Professional Committee of Shenzhen Medical Association

Where to look for more clinical knowledge of rheumatism? Come to the "doctor's station" to take a look at 👇 the references:[1] Conrad N, Verbeke G, Molenberghs G, et al.
Autoimmune diseases and cardiovascular risk: a population-based study on 19 autoimmune diseases and 12 cardiovascular diseases in 22 million individuals in the UK[J].
Lancet， 2022，400（10354）:733-743.

Source of this article: Medical Rheumatism and Immunization Channel This article author: Mu Yi This article comments + review: Chen Xinpeng Deputy Chief Physician Responsible Editor: Tangerine
Copyright Statement
This article is original, welcome to forward the circle of friends - End - Draft "Medical Rheumatology Immunity Channel" long-term recruitment online author, 1.
Rheumatology immunology clinical practical skills, misdiagnosis cases, clinical medication, interesting content; 2.
Interesting diagnosis and treatment stories of rheumatology immunologists; 3.
Heavy progress in the field of rheumatology and immunology; 4.
Others (rheumatology immunologists are interested in the content is enough).



Welcome to share the manuscript! We will provide you with competitive fees and a platform
to showcase your talents.

Submission Email: yanjin@yxj.
org.
cn (Submissions must be replied to) The medical community strives to be accurate and reliable when the published content is approved, but does not make any commitment and guarantee for the timeliness of the published content, as well as the accuracy and completeness of the cited information (if any), nor does it assume any responsibility
arising from the fact that the content is outdated, the cited information may be inaccurate or incomplete, etc.

Relevant parties are invited to verify separately when adopting or using this as a basis for decision-making
.