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Poor sleep quality and Alzheimer's disease are both related to cognitive decline, and distinguishing the effects of the two has proven to be a challenge
The results of the study were published in the October 20th issue of the "Brain" magazine
"Determining the relationship between sleep and the different stages of Alzheimer's disease has always been a challenge, but this is what you need to know in order to start designing interventions," said lead author Brendan Lucey, MD, who is the University of Washington Sleep Medicine Associate Professor of Neurology at the Center
Alzheimer's disease is the main cause of cognitive decline in the elderly, and about 70% of dementia cases are related to this
In order to clarify the different effects of sleep and Alzheimer’s disease on cognition, Lucy and her colleagues recruited some volunteers.
The researchers obtained sleep and Alzheimer's disease data for 100 participants.
Researchers found that there is a U-shaped relationship between sleep and cognitive decline
The u-type relationship is also applicable when measuring specific sleep stages, including rapid eye movement (REM), which is dreaming; and non-rapid eye movement sleep
"It is particularly interesting that not only people who sleep for a short time, but also people who sleep for a long time have a greater decline in cognitive ability," said David Holtzman, MD, professor of neurology and senior co-author
Everyone’s sleep needs are unique, and those who wake up with a short or long sleep time should not be forced to change their habits, Lucy said
"I ask many of my patients,'How's your sleep?'" said co-senior authors Beau M.
Journal Reference :
Brendan P Lucey, Julie Wisch, Anna H Boerwinkle, Eric C Landsness, Cristina D Toedebusch, Jennifer S Mcleland, Omar H Butt, Jason Hassenstab, John C Morris, Beau M Ances, David M Holtzman.