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    Home > Active Ingredient News > Antitumor Therapy > The world’s first ADC drug targeting CD19, Loncastuximab tesirine, launched a key phase II study, and completed the first patient administration in a clinical trial in China

    The world’s first ADC drug targeting CD19, Loncastuximab tesirine, launched a key phase II study, and completed the first patient administration in a clinical trial in China

    • Last Update: 2021-10-10
    • Source: Internet
    • Author: User
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    2021 Nian 9 Yue 29 days, by the way Ling Pharmaceutical and ADC Therapeutics creation of a joint venture Ling Luaidisi announced, carried out in China Loncastuximab tesirine for relapsed / diffuse large refractory B cell lymphoma ( r / r DLBCL ) A pivotal phase II clinical trial of the company completed the first patient dosing


    2021 Nian 9 Yue 29 days, by the way Ling Pharmaceutical and ADC Therapeutics creation of a joint venture Ling Luaidisi announced, carried out in China Loncastuximab tesirine for relapsed / refractory diffuse large B cell lymphoma ( lymphoma r / r DLBCL ) in a pivotal phase II clinical trial completed the first patient dosing


    This year 4 months, Loncastuximab tesirine access to the US Food and Drug Administration Administration ( Administration the FDA the FDA ) accelerated approval, becoming the first and only one targeting CD19 antibody drug conjugate ( the ADC ) drugs for at least monotherapy Adult patients with r/r DLBCL who have received 2- line or higher system therapy .


    Diffuse large B- cell lymphoma ( DLBCL ) is the most common type of adult lymphoma, a malignant tumor with great heterogeneity in clinical manifestations and prognosis


    ADC Therapeutics CEO Chris Martin Dr.


    Loncastuximab tesirine is an antibody-conjugated drug ( ADC ) targeting CD19 .


    The U.


    Xu Jianen, CEO of Linglu Idis, said: " Completing the first patient dosing of this key clinical trial is an important milestone
    .
    At the same time, we always hope to work with our partners to expand the clinical practice of Loncastuximab tesirine in Greater China and Singapore.
    Scope of application
    .
    At present, many patients in China are suffering from r/r DLBCL .
    We will, as always, strive to meet the unfulfilled needs of patients and provide effective ADC drugs to
    patients around the world who lack appropriate treatment methods .
    We look forward to and ADC Therapeutics jointly realizes the continuous development and commercialization of
    Loncastuximab tesirine in Asia .
    "

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