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    Home > Active Ingredient News > Antitumor Therapy > The Upstream and Downstream products of (S,E)-4-(dimethylamino)-N-(4-oxo-7-((tetrahydrofuran-3-yl)oxy)-3,4-dihydroquinazolin-6-yl)but-2-enamide

    The Upstream and Downstream products of (S,E)-4-(dimethylamino)-N-(4-oxo-7-((tetrahydrofuran-3-yl)oxy)-3,4-dihydroquinazolin-6-yl)but-2-enamide

    • Last Update: 2023-05-10
    • Source: Internet
    • Author: User
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    (S,E)-4-(dimethylamino)-N-(4-oxo-7-((tetrahydrofuran-3-yl)oxy)-3,4-dihydroquinazolin-6-yl)but-2-enamide is a molecule that has gained significant attention in the chemical industry due to its unique properties and potential applications.


    Upstream Products
    The upstream products for (S,E)-4-(dimethylamino)-N-(4-oxo-7-((tetrahydrofuran-3-yl)oxy)-3,4-dihydroquinazolin-6-yl)but-2-enamide include the raw materials required for its synthesis, such as dimethylamine, 4-oxo-7-((tetrahydrofuran-3-yl)oxy)-3,4-dihydroquinazolin-6-yl)but-2-ene, and other reaction components.


    The synthesis of (S,E)-4-(dimethylamino)-N-(4-oxo-7-((tetrahydrofuran-3-yl)oxy)-3,4-dihydroquinazolin-6-yl)but-2-enamide involves several steps, including the protection of the amino group, the synthesis of the but-2-ene, and the coupling of the two components.
    Each step requires the use of specific reagents and conditions to ensure the desired product is obtained.


    Downstream Products
    The downstream products for (S,E)-4-(dimethylamino)-N-(4-oxo-7-((tetrahydrofuran-3-yl)oxy)-3,4-dihydroquinazolin-6-yl)but-2-enamide include the various forms of the molecule that can be obtained through further processing or modification.


    One of the most common downstream products is the hydrochloride salt of (S,E)-4-(dimethylamino)-N-(4-oxo-7-((tetrahydrofuran-3-yl)oxy)-3,4-dihydroquinazolin-6-yl)but-2-enamide, which is often used as a pharmaceutical ingredient or in research settings.
    This salt can be prepared by treating the free base with hydrochloric acid in the presence of a solvent such as ethyl acetate or dichloromethane.


    Other downstream products include the nitrate, sulfate, and other salt forms of (S,E)-4-(dimethylamino)-N-(4-oxo-7-((tetrahydrofuran-3-yl)oxy)-3,4-dihydroquinazolin-6-yl)but-2-enamide, which can be prepared by treating the free base with the appropriate acid.
    These salts can have different physical and chemical properties compared to the free base, and may be useful in specific applications such as crystallization or as intermediate products for other chemical reactions.


    Applications
    The unique properties of (S,E)-4-(dimethylamino)-N-(4-oxo-7-((tetrahydrofuran-3-yl)oxy)-3,4-dihydroquinazolin-6-yl)but-2-enamide make it a valuable molecule in the chemical industry, particularly in the pharmaceutical and agrochemical sectors.


    In the pharmaceutical industry, (S,E)-4-(dimethylamino)-N-(4-oxo-7-((tetrahydrofuran-3-yl)oxy)-3,4-dihydroquinazolin-6-yl)but-2-enamide can be used as a building block for the synthesis of new drugs or as an active ingredient in medications.
    The molecule has been shown to have potential anti-inflammatory and anti-cancer properties, making it a promising candidate for the treatment of various diseases.


    In the agrochemical sector, (S,E)-4-(dimethylamino)-N-(4-oxo-7-((tetrahydrofuran-3-yl)oxy)-3,4-dihydroquinazolin-6-yl)but-2-enamide can be used as a herbicide or pesticide, controlling


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