The Upstream and Downstream products of Lurasidone hydrochloride

Lurasidone hydrochloride is an atypical antipsychotic agent that is used to treat various psychiatric disorders.
As a chemical compound, Lurasidone hydrochloride has a complex chemical structure and goes through several stages of processing before it can be used as a therapeutic agent.
In this article, we will explore the upstream and downstream products of Lurasidone hydrochloride, and how they are used in the chemical industry.

Upstream products of Lurasidone hydrochloride

The upstream products of Lurasidone hydrochloride refer to the raw materials and chemicals that are used in the manufacturing process.
The most important upstream products of Lurasidone hydrochloride include the following:

1. Intermediate: 2-[4-(4-Chlorophenyl)-4H-1,2,4-triazepin-1-yl]-N-(6,7-dihydro-5-methyl-2-oxo-4H-pyrano[2,3- d]pyrimidin-4-yl)acetamide

This intermediate chemical is used as the starting material for the synthesis of Lurasidone hydrochloride.
It is synthesized through a series of chemical reactions involving the protection and deprotection of functional groups, condensation reactions, and substitution reactions.

1. Precursor: 2-[4-(4-Chlorophenyl)-4H-1,2,4-triazepin-1-yl]-N-(6,7-dihydro-5-methyl-2-oxo-4H- pyrano[2,3-d]pyrimidin-4-yl)amide

This precursor is used as the starting material for the synthesis of Lurasidone hydrochloride.
It is synthesized through a series of chemical reactions involving the protection and deprotection of functional groups, condensation reactions, and substitution reactions.

1. Starting materials: 2-Amino-5-methylbenzenesulfonyl chloride, 4-Chlorophenylboronic acid, 1,2,4-Triazepine-1,4-dione, 4-Hydroxycoumarin, Pyridine-2,3-dione, N-Methylformamide, N,N-Dimethylacetamide, N-(2-Hydroxyethyl)formamide, N-Methyl-2-pyrrolidone, N-Vinylpyrrolidone

These starting materials are used as building blocks for the synthesis of Lurasidone hydrochloride.
They are carefully selected and purified to ensure their purity and reactivity.

Downstream products of Lurasidone hydrochloride

The downstream products of Lurasidone hydrochloride refer to the final products that are produced using Lurasidone hydrochloride as a raw material or intermediates.
The most important downstream products of Lurasidone hydrochloride include the following:

1. Active pharmaceutical ingredient (API): Lurasidone hydrochloride

This is the final product that is used in the treatment of psychiatric disorders.
It is synthesized using the intermediate and precursor chemicals and is purified and formulated to produce the final pharmaceutical product.

1. Finished dosage form (FDF): Lurasidone tablets

This is the final dosage form that is used in the treatment of psychiatric disorders.
It is formulated using the API and other excipients to produce the final dosage form.
The tablets are carefully designed to ensure optimal drug delivery and patient compliance.

1. Pharmaceutical intermediates: Dihydrochloride salt of Lurasidone

This intermediate chemical is used in the production of Lurasidone hydrochloride.
It is synthesized by reacting Lurasidone with hydrochloric acid to produce the dihydrochloride salt.

1. Intermediates: N-(6,7-dihydro-5-methyl-2-oxo-4