-
Categories
-
Pharmaceutical Intermediates
-
Active Pharmaceutical Ingredients
-
Food Additives
- Industrial Coatings
- Agrochemicals
- Dyes and Pigments
- Surfactant
- Flavors and Fragrances
- Chemical Reagents
- Catalyst and Auxiliary
- Natural Products
- Inorganic Chemistry
-
Organic Chemistry
-
Biochemical Engineering
- Analytical Chemistry
-
Cosmetic Ingredient
- Water Treatment Chemical
-
Pharmaceutical Intermediates
Promotion
ECHEMI Mall
Wholesale
Weekly Price
Exhibition
News
-
Trade Service
L-Valine is a crucial amino acid that plays a vital role in muscle growth and repair, which makes it an essential ingredient in many sports supplements and protein powders.
(2R,3R,11bR)-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-yl ester is an intermediate product used in the production of L-Valine.
The manufacturing process of L-Valine involves several steps, with (2R,3R,11bR)-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-yl ester as an important intermediary.
The precursor for L-Valine is usually derived from fermentation of bacteria such as Lactobacillus.
The fermentation process produces a mixture of amino acids, including L-Valine, which is then purified to obtain a pure form of the amino acid.
(2R,3R,11bR)-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-yl ester is an intermediate product that is formed during the purification process.
The esterification of L-Valine is carried out using a chemical reaction with 2-(trimethylsilyl)ethanol and hydrochloric acid.
The intermediate product is then subjected to hydrogenation to eliminate the double bond present in the Benzoxazine ring.
The Downstream Product of (2R,3R,11bR)-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-yl ester is a crucial intermediate product used in the production of L-Valine.
This product is a colorless oil with a mild characteristic odor.
The boiling point of (2R,3R,11bR)-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-yl ester is 178-180°C.
The Upstream Products of L-Valine include the raw materials needed for the production of the intermediate product.
These raw materials include fermentation broth, fermentation residues, and other chemicals used in the purification process.
The manufacturing process of L-Valine starts with the fermentation of bacteria, which produces a mixture of amino acids.
The fermentation broth is then purified to obtain a pure form of L-Valine.
The purification process involves steps such as crystallization, chromatography, and recrystallization.
The purified L-Valine is then treated with hydrogen in the presence of a metal catalyst to remove the remaining impurities.
The treated L-Valine is then subjected to hydrogenation using a Raney nickel catalyst to reduce the double bond in the Benzoxazine ring.
The reaction is carried out in the presence of an organic solvent, such as 2-(dimethylamino) ethanol, and a small amount of palladium on barium sulfate.
The product is then purified using high-performance liquid chromatography (HPLC) to obtain a pure form of the intermediate product (2R,3R,11bR)-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-yl ester.
In conclusion, (2R,3R,11bR)-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2
