The Upstream and Downstream products of Isoxazolo[4,5-b]pyridin-3-amine (9CI)

Isoxazolo[4,5-b]pyridin-3-amine, commonly referred to as 9CI, is a synthetic chemical compound that is widely used in the chemical industry.
It is an important building block in the production of various chemicals and materials.
In this article, we will explore the upstream and downstream products of 9CI and how it is used in the chemical industry.

Upstream Products

The production of 9CI involves several upstream processes, including the synthesis of precursor chemicals and the formation of the final product.
One of the key upstream products is an intermediate compound called 2-(2-chloro-6-methoxyphenyl)acetonitrile, which is synthesized through a series of chemical reactions involving chloroacetone and para-nitrophenol.
This intermediate compound is then reduced to form 2-(2-chloro-6-methoxyphenyl)ethanol, which is further transformed into 2-(2-chloro-6-methoxyphenyl)amine through a series of chemical reactions.

Another upstream product of 9CI is aniline, which is a precursor to several important chemicals, including dyes, pharmaceuticals, and rubber chemicals.
Aniline is synthesized through several chemical reactions involving benzene and nitrous acid.
The aniline is then treated with hydrochloric acid to form ortho-toluidine, which is then transformed into 2,4-diamino-6-methoxy-p-cresol through a series of chemical reactions.
This compound is then transformed into 9CI through a series of chemical reactions involving reduction, nitration, and condensation reactions.

Downstream Products

9CI is used as a building block in the production of several important chemicals and materials in the chemical industry.
One of the most important downstream products is the anti-tumor drug, Yondelis, which is used in the treatment of various types of cancer.
Yondelis is synthesized through a series of chemical reactions involving 9CI and other chemical precursors.

Another important downstream product of 9CI is the intermediate compound 2-cyano-3-dibromo-6-methoxy-p-cresol, which is used in the production of herbicides and other agricultural chemicals.
This compound is synthesized through a series of chemical reactions involving 9CI and other chemical precursors.

9CI is also used in the production of the intermediate compound 2,4-diamino-6-methoxy-p-cresol, which is used in the production of dyes, pharmaceuticals, and other chemical products.
This compound is synthesized through a series of chemical reactions involving 9CI and other chemical precursors.

Chemical Reactions

9CI undergoes several chemical reactions in the production of its upstream and downstream products.
One of the most important reactions is the reduction of 2-(2-chloro-6-methoxyphenyl)acetonitrile to form 2-(2-chloro-6-methoxyphenyl)ethanol.
This reaction is carried out using reducing agents such as lithium aluminum hydride or hydrogen in the presence of a solvent such as ether or dichloromethane.

Another important reaction is the nitration of 2-(2-chloro-6-methoxyphenyl)amine to form 9CI.
This reaction is carried out using nitrating agents such as nitric acid or nitrous acid in the presence of a solvent such as acetonitrile or water.

Conclusion

Isoxazolo[4,5-b]pyridin-3-amine (9CI) is a vers