The Upstream and Downstream products of 6-Chloro-5-hydroxy-nicotinic acid methyl ester

6-Chloro-5-hydroxy-nicotinic acid methyl ester is a chemical compound that is widely used in the pharmaceutical and chemical industries.
It is an intermediate product that is used in the production of various downstream products.
In this article, we will discuss the upstream and downstream products of 6-chloro-5-hydroxy-nicotinic acid methyl ester.

Upstream Products
The upstream products are the raw materials required for the production of 6-chloro-5-hydroxy-nicotinic acid methyl ester.
The raw materials required for the production of this compound are 6-chloro-5-hydroxy-nicotinamide and methyl iodide.
6-Chloro-5-hydroxy-nicotinamide is a derivative of nicotinamide, which is found in small amounts in certain plants and bacteria.
Methyl iodide is a colorless gas that is used as a methylating agent in organic chemistry.

Downstream Products
The downstream products are the products that are produced using 6-chloro-5-hydroxy-nicotinic acid methyl ester as an intermediate product.
The compound is used in the production of various pharmaceuticals and other chemicals.

One of the most common downstream products of 6-chloro-5-hydroxy-nicotinic acid methyl ester is N-metile-6-chloro-5-hydroxy-nicotinamide, which is used as an intermediate product in the production of certain pharmaceuticals.
It is also used in the production of agrochemicals, dyes, and other chemicals.

Another important downstream product of 6-chloro-5-hydroxy-nicotinic acid methyl ester is 6-chloro-5-hydroxy-nicotinic acid, which is used as a reagent in organic synthesis.
It is used in the production of various chemicals, including herbicides, insecticides, and fungicides.

6-chloro-5-hydroxy-nicotinic acid methyl ester is also used in the production of certain pharmaceuticals, such as anti-inflammatory drugs, anti-cancer drugs, and anti-depressant drugs.

Production of 6-chloro-5-hydroxy-nicotinic acid methyl ester
The production of 6-chloro-5-hydroxy-nicotinic acid methyl ester involves several steps.
The first step is the reaction of 6-chloro-5-hydroxy-nicotinamide with methyl iodide in the presence of a solvent, such as acetonitrile or DMF.
The reaction produces 6-chloro-5-hydroxy-nicotinic acid methyl ester, which is then purified to remove any impurities.

The purified compound is then reacted with a base, such as sodium hydroxide, to produce N-methyl-6-chloro-5-hydroxy-nicotin amide.
The reaction is carried out in the presence of a solvent, such as water or ethanol, and the product is then purified to remove any impurities.

The N-methyl-6-chloro-5-hydroxy-nicotinamide is then hydrolyzed using a strong acid, such as hydrochloric acid, to produce 6-chloro-5-hydroxy-nicotinic acid.
The reaction is carried out in the presence of a solvent, such as ethyl acetate, and the product is then purified to remove any impurities.

The purified 6-chloro-5-hydroxy-nicotinic acid is then used as an intermediate product in the production of various downstream products, such as N-methyl-6-chloro