The Upstream and Downstream products of (6-Chloro-2-methanesulfonyl-pyrimidin-4-yl)-cyclopropyl-amine

The 6-Chloro-2-methanesulfonyl-pyrimidin-4-yl)-cyclopropyl-amine is a chemical compound that is commonly used in the pharmaceutical industry as an intermediate for the synthesis of various drugs.
The compound is also known for its properties as a selective serotonin reuptake inhibitor (SSRI), which makes it a valuable building block for the development of new antidepressants and other medications that target serotonin receptors.

The upstream products of 6-Chloro-2-methanesulfonyl-pyrimidin-4-yl)-cyclopropyl-amine are the starting materials and intermediates that are used in the synthesis of the compound.
These upstream products can include raw materials like 2-methanesulfonyl-pyrimidine, cyclopropylamine, and 6-chloro-pyrimidine, as well as other intermediates like 2-chloro-pyrimidine and 4-chloro-pyrimidine.

The downstream products of 6-Chloro-2-methanesulfonyl-pyrimidin-4-yl)-cyclopropyl-amine are the finished drugs and other products that are made using the compound as a starting material.
These downstream products can include a variety of different drugs, such as antidepressants, anti-anxiety medications, and migraine treatments.

The synthesis of 6-Chloro-2-methanesulfonyl-pyrimidin-4-yl)-cyclopropyl-amine typically involves a series of chemical reactions that transform the starting materials into the desired compound.
These reactions can include substitution reactions, condensation reactions, and reduction reactions, among others.

One common synthesis route for 6-Chloro-2-methanesulfonyl-pyrimidin-4-yl)-cyclopropyl-amine involves the following steps:

1. The preparation of 2-methanesulfonyl-pyrimidine, which is made by reacting pyrimidine with methanesulfonyl chloride in the presence of a solvent like dichloromethane.
   
2. The condensation of 2-methanesulfonyl-pyrimidine with cyclopropylamine in the presence of a condensation catalyst like pyridine to form a precursor compound.
   
3. The reduction of the precursor compound using a reducing agent like hydrogen gas and a catalyst like palladium on charcoal to form 6-chloro-2-methanesulfonyl-pyrimidin-4-yl)-cyclopropyl-amine.
   
4. The purification and isolation of the product to obtain the pure compound.
   

The selection of the upstream and downstream products for a chemical synthesis depends on the specific goals of the manufacturer.
In the case of 6-Chloro-2-methanesulfonyl-pyrimidin-4-yl)-cyclopropyl-amine, the goal is typically to produce the compound as a starting material for the synthesis of pharmaceutical drugs.
The selection of upstream products and the synthesis route should therefore be designed to provide the desired starting material in a high-quality and cost-effective manner.

The downstream products of 6-Chloro-2-methanesulfonyl-pyrimidin-4-yl)-cyclopropyl-amine can vary depending on the specific application and the desired properties of the finished drug.
For example, a common downstream product of 6-Chloro-2-methanesulfonyl-pyrimidin-4-yl)-cyclopropyl-amine is