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6-Bromopyrimidin-4-amine is a versatile organic compound that finds application in various chemical processes.
One of the key applications of this compound is in the production of various pharmaceuticals, agrochemicals, and dyes.
In the chemical industry, upstream and downstream products refer to the compounds that are used as inputs and the final products that are produced, respectively.
In this article, we will discuss the upstream and downstream products of 6-bromopyrimidin-4-amine.
Upstream Products of 6-Bromopyrimidin-4-amine
The production of 6-bromopyrimidin-4-amine involves several upstream processes that require the use of various chemicals and reagents.
The primary upstream products of 6-bromopyrimidin-4-amine are the starting materials required for its synthesis.
These materials include pyrimidine-5-carboxylic acid, chloroform, hydrogen chloride, and bromine.
Pyrimidine-5-carboxylic acid is a key intermediate in the synthesis of 6-bromopyrimidin-4-amine.
It is obtained by the reaction of pyrimidine-5-amine with carbon dioxide under acidic conditions.
Chloroform is used as a solvent for the reaction.
Hydrogen chloride is used to acidify the reaction mixture, and bromine is used as a reagent to introduce bromine atoms onto the pyrimidine ring.
The addition of bromine atoms leads to the formation of 6-bromopyrimidin-4-carboxylic acid, which is then converted to 6-bromopyrimidin-4-amine through a series of chemical reactions.
Downstream Products of 6-Bromopyrimidin-4-amine
The primary downstream product of 6-bromopyrimidin-4-amine is the pharmaceutical drug S-1, which is used to treat various types of cancer.
S-1 is a combination therapy that includes 6-bromopyrimidin-4-amine as one of its active ingredients.
Other downstream products of 6-bromopyrimidin-4-amine include agrochemicals, dyes, and other pharmaceutical agents.
Agrochemicals such as herbicides and pesticides can be synthesized using 6-bromopyrimidin-4-amine as a precursor.
Herbicides are used to kill unwanted plants, while pesticides are used to control pests and other unwanted organisms.
Dyes are another important downstream product of 6-bromopyrimidin-4-amine.
Dyes are used to color various products, including textiles, plastics, and food products.
The dye industry is a large and growing market, and the production of dyes requires a range of chemical intermediates, including 6-bromopyrimidin-4-amine.
6-Bromopyrimidin-4-amine is also used in the production of other pharmaceuticals, including immunosuppressants and anti-inflammatory agents.
These drugs are used to treat a variety of medical conditions, including autoimmune diseases, cancer, and inflammation.
In conclusion, 6-bromopyrimidin-4-amine is a versatile intermediate that is used in the production of various chemicals and pharmaceuticals.
The production of this compound involves several upstream processes, including the synthesis of pyrimidine-5-carboxylic acid, chloroform, hydrogen chloride, and bromine.
The primary downstream product of 6-bromopyrimidin-4-