The Upstream and Downstream products of 6-[4-Aminophenyl]pyridazin-3(2H)-one

6-[4-Aminophenyl]pyridazin-3(2H)-one, commonly referred to as APP, is a benzoxazepine derivative that has found use in various industrial applications.
In the chemical industry, APP is utilized as an intermediate in the synthesis of a variety of downstream products.
These downstream products can be further processed to produce a range of commercial products that are used in various industries, including pharmaceuticals, agrochemicals, and consumer goods.

One of the most well-known downstream products of APP is 2,4-Dichlorophenoxyacetic acid (2,4-D), which is widely used as a herbicide.
The synthesis of 2,4-D from APP involves several steps, including the conversion of APP to 4-Amino-6-Chloropyridazine (4-ACP), followed by the hydrolysis of 4-ACP to yield 4-Chloro-6-hydroxy-pyridazine (4-CHP).
This intermediate can then be used to produce 2,4-D through a series of chemical reactions.

Another significant downstream product of APP is the herbicide MCPA (4-Chloro-2-Methylphenoxyacetic acid).
The synthesis of MCPA from APP follows a similar route to that of 2,4-D, involving the conversion of APP to 4-ACP and subsequent hydrolysis to 4-CHP.
MCPA is widely used in agriculture to control weeds and unwanted plant growth.

In addition to herbicides, APP can also be used as an intermediate in the synthesis of pharmaceuticals.
One such product is the antiplatelet drug Ticagrelor, which is used to prevent blood clots from forming in patients with cardiovascular disease.
The synthesis of Ticagrelor from APP involves several steps, including the conversion of APP to 4-Amino-6-Chloropyridazine (4-ACP) and subsequent chemical transformations to yield the final product.

In the agrochemical industry, APP is used as an intermediate in the synthesis of a range of pesticides and fungicides.
One such product is the fungicide Chlorothalonil, which is used to control fungal diseases in crops.
The synthesis of Chlorothalonil from APP involves several steps, including the conversion of APP to 4-Amino-6-Chloropyridazine (4-ACP) and the subsequent transformation of 4-ACP to yield the final product.

In addition to its use in the production of downstream products, APP has also found application in the field of materials science.
It has been used as a monomer in the synthesis of poly(p-phenylene) vinylene (PPV), a polymer that has applications in organic electronics and plastic electronics.

In conclusion, 6-[4-Aminophenyl]pyridazin-3(2H)-one (APP) is a versatile intermediate that can be converted into a range of downstream products through a series of chemical reactions.
These downstream products have applications in various industries, including pharmaceuticals, agrochemicals, and materials science.
The synthesis of these products involves several steps and requires the use of specialized equipment and chemical reagents.
The production of these downstream products provides a significant economic impact on the chemical industry and has a wide range of applications in various industries.