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5-Iodo-2-(phenylmethyl)-3(2H)-pyridazinone is an important intermediate in the chemical industry, which is widely used as a building block for the synthesis of various pharmaceuticals, agrochemicals, and other chemical products.
The upstream and downstream products of this intermediate can vary depending on the specific application, but some common examples are discussed in this article.
Upstream Products
The upstream products of 5-Iodo-2-(phenylmethyl)-3(2H)-pyridazinone can include the raw materials required for its synthesis, such as iodine, phenylmethylamine, and 3(2H)-pyridazinone.
The manufacturing process typically involves several steps, including iodination, sulfurization, and reductive amination.
These steps require the use of various chemical reagents and solvents, as well as specialized equipment such as reactors, condensers, and dryers.
Downstream Products
The downstream products of 5-Iodo-2-(phenylmethyl)-3(2H)-pyridazinone can include a wide range of chemical products, depending on the specific application.
For example, this intermediate can be used in the synthesis of antibiotics, anti-inflammatory drugs, and herbicides.
In addition, it can also be converted into other intermediates or final products such as dyes, plastics, or surfactants.
One common application of 5-Iodo-2-(phenylmethyl)-3(2H)-pyridazinone is in the production of antibiotics such as erythromycin, which is used to treat a variety of bacterial infections.
The synthesis of erythromycin involves several steps, including the synthesis of the macrolide ring, the addition of the various substituents, and the formation of the lactone ring.
5-Iodo-2-(phenylmethyl)-3(2H)-pyridazinone is used in this process as a key intermediate for the synthesis of the macrollide ring.
Another application of 5-Iodo-2-(phenylmethyl)-3(2H)-pyridazinone is in the production of anti-inflammatory drugs such as celecoxib, which is used to treat pain, inflammation, and other symptoms associated with various conditions such as arthritis and menstrual cramps.
Celecoxib is synthesized by a multi-step process that involves the synthesis of several key intermediates, including 5-Iodo-2-(phenylmethyl)-3(2H)-pyridazinone.
5-Iodo-2-(phenylmethyl)-3(2H)-pyridazinone can also be used in the production of herbicides such as imazamox, which is used to control weeds in crops such as soybeans, corn, and cotton.
Imazamox is synthesized by a multi-step process that involves the synthesis of several key intermediates, including 5-Iodo-2-(phenylmethyl)-3(2H)-pyridazinone.
In addition to these specific applications, 5-Iodo-2-(phenylmethyl)-3(2H)-pyridazinone can also be used in the synthesis of other chemical products such as dyes, plastics, and surfactants.
Production and Purification
The production of 5-Iodo-2-(phenylmethyl)-3(2H)-pyridazinone typically involves several steps, including iodination, sulfurization, and reductive amination.
These steps require the use of various chemical reagents and solvents, as well as specialized equipment such as reactors, condensers, and dryers.
The pur