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    Home > Medical News > Medical World News > The Upstream and Downstream products of 5-Bromo-2-(methylthio)pyrimidine-4-carboxylic acid

    The Upstream and Downstream products of 5-Bromo-2-(methylthio)pyrimidine-4-carboxylic acid

    • Last Update: 2023-05-13
    • Source: Internet
    • Author: User
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    5-Bromo-2-(methylthio)pyrimidine-4-carboxylic acid is a compound that is used as an intermediate in the production of various chemicals and pharmaceuticals.
    It is produced through a series of chemical reactions that involve several steps, each of which is carried out in a specific order.
    The process of producing 5-Bromo-2-(methylthio)pyrimidine-4-carboxylic acid is known as the chemical synthesis route.


    The Upstream Products of 5-Bromo-2-(methylthio)pyrimidine-4-carboxylic acid are the raw materials that are used in the production of the compound.
    The main Upstream Products include methyl thiophenate, 2-bromopyrimidine-5-carboxylic acid, and potassium hydroxide.
    Methyl thiophenate is prepared by reacting thiophenol with methyl iodide in the presence of a Lewis acid catalyst.
    2-bromopyrimidine-5-carboxylic acid is produced by treating 2-bromopyrimidine-5-amide with hydrogen chloride in the presence of a Lewis acid catalyst.
    Potassium hydroxide is obtained by electrolysis of water.


    The Downstream Products of 5-Bromo-2-(methylthio)pyrimidine-4-carboxylic acid are the chemicals and pharmaceuticals that are produced using the compound as an intermediate.
    The main Downstream Products include anti-inflammatory drugs, antiviral drugs, and anticancer drugs.
    The compound is used in the production of these drugs because of its unique chemical properties, which make it a valuable building block for the synthesis of various pharmaceuticals.


    The production of 5-Bromo-2-(methylthio)pyrimidine-4-carboxylic acid involves several steps, each of which is carried out in a specific order.
    The first step in the production process is the preparation of methyl thiophenate, which is used as the starting material for the synthesis of 2-bromopyrimidine-5-carboxylic acid.
    This is followed by the treatment of 2-bromopyrimidine-5-carboxylic acid with hydrogen chloride in the presence of a Lewis acid catalyst to produce 2-bromopyrimidine-5-amide.
    The next step is the treatment of 2-bromopyrimidine-5-amide with potassium hydroxide in the presence of a Lewis acid catalyst to produce 5-bromo-2-(methylthio)pyrimidine-4-carboxylic acid.


    The production of 5-Bromo-2-(methylthio)pyrimidine-4-carboxylic acid is an important process in the chemical industry, as it is used as an intermediate in the production of various chemicals and pharmaceuticals.
    The compound is produced through a series of chemical reactions that involve several steps, each of which is carried out in a specific order.
    The production process is a complex one that requires the use of several chemicals and reagents, as well as specialized equipment and conditions.
    The purity and quality of the final product play a crucial role in the efficacy and safety of the final drug product.
    Therefore, the production process must be designed and executed with great care and attention to detail.


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