The Upstream and Downstream products of 4-Pyridazinecarboxylic acid, 6-chloro-, methyl ester

4-Pyridazinecarboxylic acid, 6-chloro-, methyl ester is a chemical compound that is commonly used as an intermediate in the production of various chemicals and pharmaceuticals.
It is also known as 4-pyridazinecarboxylic acid, 6-chloromethyl ester or simply 4-PC6-Me.

Upstream Products
The production of 4-Pyridazinecarboxylic acid, 6-chloro-, methyl ester involves several upstream processes, which are responsible for extracting, isolating, and purifying the various components required for the production of the final product.

One of the key upstream products is pyridine-2,6-dicarboxylic acid, which is a precursor to 4-Pyridazinecarboxylic acid, 6-chloro-, methyl ester.
Pyridine-2,6-dicarboxylic acid is typically produced through a chemical reaction involving the condensation of pyridine-2,6-diamine and sebacic acid.

Another upstream product is 4-chloromethylpyridine, which is used in the production of 4-Pyridazinecarboxylic acid, 6-chloro-, methyl ester.
This compound is typically produced through a reaction between chloroform and pyridine.

Downstream Products
The primary downstream product of 4-Pyridazinecarboxylic acid, 6-chloro-, methyl ester is 4-Pyridazinecarboxylic acid, 6-chloro-, methyl ester itself, which is used as an intermediate in the production of various chemicals and pharmaceuticals.

One of the most common downstream products is the anti-cancer drug Nexavar, which is a brand name for the combination of two chemotherapy drugs, sorafenib and sunitinib.
Nexavar is used to treat several types of cancer, including kidney cancer, liver cancer, and thyroid cancer.

Another downstream product is the immunosuppressant drug Rapamune, which is used to prevent the rejection of transplanted organs in patients.
Rapamune is a macrolide immunosuppressant that inhibits the production of T cells, which are a type of white blood cell that plays a critical role in the immune system.

Other downstream products include several chemical compounds that are used in a variety of industrial applications, such as plastics, textiles, and dyes.

Uses and Applications
4-Pyridazinecarboxylic acid, 6-chloro-, methyl ester is used as an intermediate in the production of several chemicals and pharmaceuticals, making it a versatile and valuable compound in the chemical industry.

One of the most common uses of 4-Pyridazinecarboxylic acid, 6-chloro-, methyl ester is in the production of Nexavar, which is a combination of two chemotherapy drugs used to treat several types of cancer.

4-Pyridazinecarboxylic acid, 6-chloro-, methyl ester is also used in the production of Rapamune, which is an immunosuppressant drug used to prevent the rejection of transplanted organs in patients.

Other uses of 4-Pyridazinecarboxylic acid, 6-chloro-, methyl ester include the production of various chemical compounds that are used in a variety of industrial applications, such as plastics, textiles, and dyes.

Economic Impact
The production of 4-Pyridazinecarboxylic acid, 6-chloro-, methyl ester and its conversion into downstream products such as Nexavar and Rapamune has a