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4-Chloro-N,N-dimethyl-pyridine-2-carboxamide, also known as 4-Cl-P2C, is an organic compound that is commonly used in the chemical industry.
It is a derivative of pyridine-2-carboxamide, which itself is a derivative of the naturally occurring compound pyridine.
Upstream Products
The production of 4-Cl-P2C involves several upstream processes, including the synthesis of precursor compounds and their subsequent transformation into the final product.
One of the key precursor compounds used in the production of 4-Cl-P2C is dimethylformamide (DMF), which is a colorless liquid with a strong, unpleasant odor.
DMF is a common solvent used in the chemical industry and is also used as a precursor in the production of other chemicals.
To synthesize 4-Cl-P2C, DMF is first reacted with chloroform to form N,N-dimethyl-chlorformamide (DMCA).
This reaction is typically carried out in the presence of a strong acid catalyst, such as hydrochloric acid or sulfuric acid.
The resulting DMCA is then hydrolyzed in the presence of an alkali, such as sodium hydroxide, to generate dimethylamine and N-chloroformanilide.
These two compounds are then reacted with each other in the presence of a condensing agent, such as a base or another strong acid, to form N-chloro-N'-methylpyridinium chloride.
This compound is then reacted with a primary amine, such as N-methylaniline, to form the final product, 4-Cl-P2C.
Downstream Products
Once 4-Cl-P2C has been synthesized, it can be transformed into a variety of downstream products through a range of chemical reactions.
One common reaction involves the reduction of 4-Cl-P2C to form 4-aminopyridine-2-carboxamide (4-AP2C), which is used as a building block for the synthesis of various pharmaceuticals and agrochemicals.
4-Cl-P2C can also be converted into other derivatives through reactions with other compounds.
For example, it can be reacted with an aldehyde, such as formaldehyde, in the presence of a strong acid catalyst, such as sulfuric acid, to form a pyrrolidone derivative.
This derivative can then be further transformed into other chemicals, such as N-substituted piperidines, through a series of chemical reactions.
4-Cl-P2C can also be used as a precursor for the synthesis of polyamides, which are polymers used in a variety of applications, including textiles, packaging, and engineering materials.
The polymerization of 4-Cl-P2C involves the reaction of the monomer with a diamine, such as 4,4'-oxydianiline, in the presence of a catalyst, such as tetramethylguanidine.
The resulting polymer can be further processed and shaped into the desired form.
Applications
4-Cl-P2C and its downstream derivatives are used in a variety of applications in the chemical industry.
Some of the most common applications include:
- Pharmaceuticals: 4-Cl-P2C and its derivatives are used as building blocks for the synthesis of various pharmaceuticals, including analgesics, muscle relaxants, and anti-inflammatory drugs.
- Agrochemicals: 4-Cl-P2C and its derivatives are used as active ingredients in various agrochemicals, such as herbicides, insecticides, and fungicides.
- Polyamides: 4
