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    Home > Medical News > Medical World News > The Upstream and Downstream products of 4-CHLORO-5-METHOXYPYRIDAZIN-3(2H)-ONE

    The Upstream and Downstream products of 4-CHLORO-5-METHOXYPYRIDAZIN-3(2H)-ONE

    • Last Update: 2023-05-09
    • Source: Internet
    • Author: User
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    The chemical industry plays a crucial role in the production of various chemicals that are used in various applications.
    One such chemical is 4-Chloro-5-methoxypyridazin-3(2H)-one, which is commonly used as an intermediate in the production of agrochemicals, pharmaceuticals, and other chemical products.


    Upstream Products


    The upstream products of 4-Chloro-5-methoxypyridazin-3(2H)-one are the raw materials required for its production.
    These raw materials include 4-chloro-5-methoxypyridazin-2(1H)-one, which is obtained from the reaction of 4-methoxy-6-nitroquinoline with chloroacetyl chloride, and 3-hydroxy-5-methoxybenzaldehyde, which is obtained from the hydrolysis of 3-nitro-5-methoxybenzene.


    The production of 4-chloro-5-methoxypyridazin-2(1H)-one involves the reaction of 4-methoxy-6-nitroquinoline with chloroacetyl chloride in the presence of a Lewis acid catalyst, such as aluminum chloride.
    The reaction results in the formation of the 2-chloro-5-methoxy-6-nitroquinoline intermediate, which undergoes hydrolysis in the presence of water to produce 3-hydroxy-5-methoxybenzaldehyde.


    Downstream Products


    The downstream products of 4-Chloro-5-methoxypyridazin-3(2H)-one are the chemical products that are produced using this intermediate.
    The most common downstream product of 4-Chloro-5-methoxypyridazin-3(2H)-one is 2,6-dichloro-4H-pyrido[1,2-b]pyrazin-3-one, which is commonly used as an herbicide.


    The production of 2,6-dichloro-4H-pyrido[1,2-b]pyrazin-3-one involves the reaction of 3-hydroxy-5-methoxybenzaldehyde with chloroacetyl chloride in the presence of a Lewis acid catalyst, such as aluminum chloride.
    The reaction results in the formation of 2-chloro-6-hydroxy-4H-pyrido[1,2-b]pyrazine-3-one, which undergoes further processing to produce the final product.


    Other Downstream Products


    In addition to 2,6-dichloro-4H-pyrido[1,2-b]pyrazin-3-one, 4-Chloro-5-methoxypyridazin-3(2H)-one can also be used in the production of other chemicals, including pharmaceuticals and agrochemicals.
    For example, 4-Chloro-5-methoxypyridazin-3(2H)-one can be transformed into 4-chloro-5-(2,6-dinitrophenyl)-2H-pyrido[1,2-b]pyrazin-3-one, which is a commonly used herbicide.


    Market and Applications


    The demand for 4-Chloro-5-methoxypyridazin-3(2H)-one and its downstream products has been increasing in recent years due to the growing demand for agrochemicals and pharmaceuticals.
    The production of 4-Chloro-5-methoxypyridaz


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