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4-BROMO-N-[2-(TBDMSO)ETHYL]BENZENESULFONAMIDE is a chemical compound that is commonly used in the production of a variety of downstream products in the chemical industry.
However, it is important to note that the production of 4-BROMO-N-[2-(TBDMSO)ETHYL]BENZENESULFONAMIDE itself is a complex process that involves several upstream products.
One of the primary upstream products used in the production of 4-BROMO-N-[2-(TBDMSO)ETHYL]BENZENESULFONAMIDE is benzene.
Benzene is a naturally occurring aromatic hydrocarbon that is widely used as a starting material in the production of a variety of chemicals.
It is extracted from petroleum and natural gas, and is also produced synthetically through the Birch reduction process.
Once benzene has been obtained, it is then converted into nitrobenzene through a process known as nitration.
Nitration involves the addition of nitric acid to benzene, which results in the formation of nitrobenzene.
This intermediate is then used in the next step of the process to produce 4-bromo-N-[2-(TBDMSO)ethyl]benzenesulfonamide.
The next upstream product in the production of 4-BROMO-N-[2-(TBDMSO)ETHYL]BENZENESULFONAMIDE is 2,2'-azobis(2-methylpropionamidine)dichloride, also known as TBDMS-Cl.
TBDMS-Cl is a highly reactive compound that is commonly used as a coupling agent in a variety of organic synthesis reactions.
It is produced by the reaction of 2,2'-azobis(2,4-dimethylvaleronitrile) with chlorine gas.
The final upstream product in the production of 4-BROMO-N-[2-(TBDMSO)ETHYL]BENZENESULFONAMIDE is (2-bromo-6-methylbenzene)diisopropylamine.
This compound is used as a catalyst in the production of 4-BROMO-N-[2-(TBDMSO)ETHYL]BENZENESULFONAMIDE.
It is produced by reacting 2-bromo-6-methylbenzene with diisopropylamine in the presence of a catalyst, such as aluminum chloride.
Once these upstream products have been obtained and purified, they can be combined in a series of reactions to produce 4-BROMO-N-[2-(TBDMSO)ETHYL]BENZENESULFONAMIDE.
The first step in the production of this compound involves the reaction of 2,2'-azobis(2-methylpropionamidine)dichloride with benzene in the presence of a catalyst, such as aluminum chloride.
This results in the formation of an azo compound, which is then treated with sodium hydride and 1,3-dimethyl-3-oxobutane to produce 4-bromo-N-[2-(TBDMSO)ethyl]benzene-1,4-diamine.
The next step in the production of 4-BROMO-N-[2-(TBDMSO)ETHYL]BENZENESULFONAMIDE involves the reaction of this diamine with 2-bromo-6-methylbenzene-diisopropylamine in the presence of a solvent, such as N,N