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The 4-Amino-5-bromo-2-chloropyrimidine, also known as 4-ABP, is an important chemical intermediate that is widely used in the pharmaceutical, agrochemical, and other industries.
The chemical structure of 4-ABP is shown below:
4-Amino-5-bromo-2-chloropyrimidine
As a chemical intermediate, 4-ABP can be converted into a variety of downstream products through a series of chemical reactions.
In this article, we will explore the upstream and downstream products of 4-ABP in the chemical industry.
Upstream Products of 4-ABP
The upstream products of 4-ABP are the raw materials and intermediates that are used to produce it.
The following are some examples of upstream products of 4-ABP:
- Pyrimidine-5-carbaldehyde: This is an intermediate that is used in the production of 4-ABP.
Pyrimidine-5-carbaldehyde is synthesized by the reduction of pyrimidine-5-one, which is derived from the condensation of uracil and thymine. - N-Bromosuccinimide (NBS): NBS is a reagent that is used in the synthesis of 4-ABP.
It is used to introduce bromine atoms into the pyrimidine ring of the intermediate, which leads to the formation of 4-ABP. - N-Chlorosuccinimide (NCS): NCS is another reagent that is used in the synthesis of 4-ABP.
It is used to introduce chlorine atoms into the pyrimidine ring of the intermediate, which leads to the formation of 4-ABP.
Downstream Products of 4-ABP
The downstream products of 4-ABP are the chemical compounds that are derived from it through a series of chemical reactions.
The following are some examples of downstream products of 4-ABP:
- 5-Amino-4-chloropyrimidine: This is a downstream product of 4-ABP that is used in the production of pharmaceuticals and agrochemicals.
It is synthesized by the reduction of 4-ABP, which leads to the formation of the amino group. - 5-Amino-4-bromopyrimidine: This is another downstream product of 4-ABP that is used in the production of pharmaceuticals and agrochemicals.
It is synthesized by the reduction of 4-ABP, followed by the introduction of bromine atoms into the pyrimidine ring. - 5-Amino-4-chloro-2-nitro-pyrimidine: This is a downstream product of 4-ABP that is used in the production of agrochemicals.
It is synthesized by the nitration of 5-amino-4-chloropyrimidine, followed by the reduction of the nitro group.
Applications of 4-ABP and Its Derivatives
The derivatives of 4-ABP, such as 5-amino-4-bromopyrimidine and 5-amino-4-chloro-2-nitro-pyrimidine, are widely used in the pharmaceutical and agrochemical industries.
They are used in the production of various medicines, pesticides, and other chemicals.
4-ABP itself is used as an intermediate in the production of pharmaceuticals, such as antibiotics and anti-inflammatory drugs.
It is also used in the production of agrochemicals, such as herbicides
