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4,5-Dibromo-2-phenyl-3(2H)-pyridazinone is an organic compound that is commonly used in the chemical industry.
This compound is an important intermediate in the production of various chemicals and drugs, and its demand is growing steadily due to its increasing applications in various industries.
Upstream Products
The upstream products of 4,5-dibromo-2-phenyl-3(2H)-pyridazinone are the raw materials required for its manufacturing.
These raw materials include various chemicals and reagents that are used in the production process.
Some of the commonly used upstream products include hydrogen bromide, acetic acid, sodium hydroxide, sodium bromide, and phenylboronic acid.
Downstream Products
The downstream products of 4,5-dibromo-2-phenyl-3(2H)-pyridazinone are the chemicals and drugs that are produced using this compound as an intermediate.
The demand for these downstream products is high in various industries such as pharmaceuticals, agrochemicals, and cosmetics.
Some of the commonly used downstream products include antibiotics, anti-inflammatory drugs, anti-malarial drugs, and pesticides.
Manufacturing Process
The manufacturing process of 4,5-dibromo-2-phenyl-3(2H)-pyridazinone involves several steps, which are carried out in a controlled environment to ensure the quality of the final product.
The process typically involves the following steps:
- Preparation of the substrate: The substrate, which is phenylboronic acid, is prepared by reacting boric acid with phenyl chloride.
- Bromination reaction: The prepared substrate is then treated with hydrogen bromide gas in the presence of a catalyst such as zinc bromide.
This reaction results in the formation of 4,5-dibromo-2-phenyl-3(2H)-pyridazinone. - Purification and isolation: The product is then purified and isolated by crystallization or other purification methods.
- Hydrolysis: The final product is then treated with water and sodium hydroxide to remove any remaining bromide ions.
Quality Control
Quality control is a critical aspect of the manufacturing process of 4,5-dibromo-2-phenyl-3(2H)-pyridazinone.
The quality of the final product depends on the purity and accuracy of the raw materials used and the efficiency of the manufacturing process.
Quality control checks are carried out at various stages of the manufacturing process to ensure that the final product meets the required standards.
These checks include chemical analysis, physical testing, and microbiological testing.
Regulatory Compliance
The manufacturing process of 4,5-dibromo-2-phenyl-3(2H)-pyridazinone is regulated by various government agencies, such as the FDA in the US and the EMA in the EU.
The manufacturers of this compound must comply with various regulations and guidelines to ensure the safety and efficacy of the final product.
These regulations include good manufacturing practices (GMP), good laboratory practices (GLP), and environmental regulations.
Conclusion
4,5-dibromo-2-phenyl-3(2H)-pyridazinone is an important intermediate in the chemical industry, and its demand is increasing due to its wide range of applications in various industries.
The upstream and downstream products of this compound include various chemicals and drugs, and the manufacturing process involves several steps that are carried out in a controlled environment to ensure the quality of the final product.
Quality control and regulatory compliance are essential aspects of the manufacturing process, and the manufactur